Sepsis
Conditions
Interventions
Experimental Group:Routine treatment for sepsis + Xuanbai Shengmai Decoction
Sponsors
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Meets the diagnostic criteria for sepsis; (2) Aged 18–80 years; (3) Voluntarily participates in the study and has signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Pregnant or lactating women; (2) Shock or death occurring within 48 hours of admission; (3) Vegetative state; (4) Confirmed or highly suspected acute infectious diseases, such as active viral hepatitis or active pulmonary tuberculosis; (5) Allergy to the active ingredient or excipients of the investigational drug; (6) Participation in any clinical intervention trial within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day mortality rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sequential Organ Failure Assessment;Acute Physiology and Chronic Health Evaluation II;Severe complication incidence rate;Hospitalization Days;Blood Oxygen Saturation;Partial pressure of oxygen in the artery;Partial pressure of arterial carbon dioxide;White blood cell count;Neutrophil percentage;lymphocyte count;C-reactive protein;Erythrocyte Sedimentation Rate;D-dimer;Troponin I;Troponin T;Brain natriuretic peptide;Serum Creatinine;Urea nitrogen;Alanine Aminotransferase;Glutamic-oxaloacetic transaminase;Blood Proteomics;Blood Metabolomics;Blood Single-Cell Sequencing Analysis;Fecal Metabolomics;Fecal microbiota diversity analysis; | — |
Countries
China
Contacts
Public ContactYang Siwen
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Outcome results
None listed