IgAN
Conditions
Interventions
The integrated traditional Chinese and Western medicine treatment group:The Yiqi Peiyuan Formula combined with basic Western medical treatment
Sponsors
Punan Hospital, Pudong New Area, Shanghai
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Patients diagnosed with IgA nephropathy through renal biopsy; 2) Patients who have been regularly followed up at the participating research center; 3) 18-75 years old; 4) Within 3 months before the start of the study, no steroid or immunosuppressive agent treatment was used; 5) Within 1 month before the start of the study, standard treatment had been applied: lifestyle improvement + the maximum tolerated dose of ACEI/ARB for the patient + active control of blood pressure, blood sugar and blood lipids; 6) 24-hour urine protein greater than 0.5g/d; 7) Signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Expected survival time shorter than 3 months; 2) Known allergy to the test drug; 3) Secondary IgA nephropathy; 4) Unable to follow up regularly; 5) eGFR less than 15 ml/min; 6) Acute renal failure patients; 7) Patients with mental disorders; 8) Pregnant or lactating women; 9) Severe infection, uncontrolled water and electrolyte disorders that cannot be effectively controlled; 10) Patients currently participating in other drug clinical trials or having participated in other clinical trials within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum creatinine;urea nitrogen;Glomerular Filtration Rate;24-hour urine protein quantification;Urine albumin to creatinine ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| Traditional Chinese Medicine Syndrome Indicators; | — |
Countries
China
Contacts
Public ContactLumin Tang
Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University
Outcome results
None listed