amnestic Mild Cognitive Impairment
Conditions
Interventions
amnestic Mild Cognitive Impairment:Acupuncture points plus healthy living instructions
amnestic Mild Cognitive Impairment:Acupuncture non-acupuncture plus healthy living instructions
amnestic Mild Cognitive Impairment:No intervention plus healthy living instructions
Sponsors
Wang Feng
Eligibility
Sex/Gender
All
Age
55 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients were recruited who were first diagnosed with aMCI in the outpatient clinic of the Department of Acupuncture and Moxibustion of the First Hospital Affiliated to Heilongjiang University of Traditional Chinese Medicine from January 2025 to April 2025. aMCI diagnostic criteria were based on the Chinese expert consensus on assessment of cognitive impairment in the elderly and Petersen's diagnostic criteria. The diagnostic criteria of aMCI refer to the "Chinese expert consensus on assessment of cognitive impairment in the elderly" and Petersen's diagnostic criteria. (1) The patient was 55-75 years old; (2) complained of memory loss and had objective evidence of memory loss; (3) overall cognitive function was unaffected, and the ability to perform daily activities was normal; (4) there was no dementia, with a clinical dementia score of 0.5, of which the memory score was at least 0.5; (5) the score on the mini-mental state examination (MMSE) was at least 0.5; and (6) the patient had no dementia, with a clinical dementia score of 0.5, and the memory score was at least 0.5. examination (MMSE) score between 24 and 30, and Montreal Cognitive Assessment (MoCA) score between 18 and 26.
Exclusion criteria
Exclusion criteria: The following patients were excluded from recruitment: (1) subjects with serious adverse events that prevented them from proceeding to the next step of the trial; (2) those with sudden onset of cerebrovascular disease or craniocerebral trauma during the course of the trial; (3) those who were unable to persist in completing the acupuncture treatment; (4) those with incomplete clinical and imaging data; (5) those with poor compliance; and (6) those with other uncontrollable factors or who withdrew from the trial on their own.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting-state oxygen level functional magnetic resonance imaging; | — |
Secondary
| Measure | Time frame |
|---|---|
| mini-mental state examination;montreal cognitive assessment;Gray matter volume;white matter dispersion;Clinical Dementia Rating Scale;Overall Recession Scale;Activities of Daily Living Scale;informant questionaire on cognitive decline in the elderly;Wechsler memory scale; | — |
Countries
China
Contacts
Public ContactWang Feng
The First Hospital Affiliated to Heilongjiang University of Traditional Chinese Medicine
Outcome results
None listed