Chronic fatigue syndrome
Conditions
Sponsors
Shuguang Hospital affiliated to Shanghai University of TCM
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1)Age range from 20 to 60 years old regardless of gender; (2)According to the consensus on CFS diagnosis established by IOM; (3)Right-handed; (4)A change in bowel habits within the past month, including frequency, consistency, or defecation process; specifically, =3 bowel movements per day or =3 per week. Diarrhea may be accompanied by symptoms such as abdominal cramping or urgency, while constipation may present as difficulty in defecation or a sensation of incomplete evacuation; (5)No use of any interventions that may affect study outcomes within the past month, including Western medicine, Chinese patent medicines, herbal decoctions, or acupuncture; (6)Normal language comprehension and communication abilities, with the capacity to understand and complete questionnaires; (7)Informed consent and voluntarily sign the Informed Consent Form.
Exclusion criteria
Exclusion criteria: (1)Fatigue symptoms do not result in substantial impairment in occupational functioning, education, social activities, recreational activities, or activities of daily living; (2)Presence of severe dysfunction in vital organs, including the heart, brain, liver, or kidney;History of tumors, neurological disorders, or active infections; (3)Diagnosed psychiatric disorders or major depressive disorder, defined as a Self-Rating Depression Scale (SDS) score = 63; (4)Pregnant or planning to become pregnant, or currently breastfeeding; (5)Contraindications to magnetic resonance imaging (MRI), such as the presence of a cardiac pacemaker, neurostimulator, metallic implants or foreign bodies (e.g., intrauterine device), or insulin pump; (6)Severely obese individuals: Body Mass Index (BMI) > 45, BMI = weight (kg) / height (m)²; (7)Other conditions deemed inappropriate for participation in this study by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatigue Scale-14; | — |
Secondary
| Measure | Time frame |
|---|---|
| 36-Item Short Form Health Survey;Visual Analogue Scale ;Pittsburgh Sleep Quality Index ;Self-Rating Anxiety Scale;Self-Rating Depression Scale;Gastrointestinal Symptom Rating Scale;Bristol stool typing scale;Hand Grip Strength Test; | — |
Countries
China
Contacts
Public ContactWenzonglin
Shuguang Hospital Shanghai University of Traditional Chinese Medicine
Outcome results
None listed