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Application of Transcutaneous Electrical Acupoint Stimulation Combined with Tropisetron in Preventing Postoperative Nausea and Vomiting in Patients Undergoing Orthognathic Surgery

Application of Transcutaneous Electrical Acupoint Stimulation Combined with Tropisetron in Preventing Postoperative Nausea and Vomiting in Patients Undergoing Orthognathic Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025002177
Enrollment
Unknown
Registered
2025-11-08
Start date
2025-12-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Nausea and Vomiting

Interventions

A group:Transcutaneous Electrical Acupoint Stimulation and tropisetron
B group:Tropisetron

Sponsors

Peking University School and Hospital of Stomatology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged between 18 and 60 years. 2. Scheduled to undergo elective bimaxillary orthognathic surgery. 3. With an Apfel score of = 3 points (indicating high risk for PONV). 4. Classified as American Society of Anesthesiologists (ASA) physical status I or II. 5. Having provided written informed consent.

Exclusion criteria

Exclusion criteria: 1. Administration of antiemetics or steroids within 24 hours prior to surgery. 2. Coexisting gastrointestinal diseases (e.g., gastroparesis, intestinal obstruction). 3. Severe cardiac arrhythmia or presence of a cardiac pacemaker. 4. Skin breakdown or infection at the intended electrical stimulation sites. 5. Long-term use of psychotropic medications (e.g.,SSRI, SNRI). 6. Pregnant or lactating women. 7. History of needle syncope or intolerance to electrical stimulation.

Design outcomes

Primary

MeasureTime frame
The incidence of postoperative nausea and vomiting within 24 hours.;

Secondary

MeasureTime frame
The incidence of postoperative nausea and vomiting within 48 hours.;Recovery time of gastrointestinal function after surgery;Quality of Recovery Score; ?Perioperative Patient Comfort Satisfaction Score;Adverse events included the rates of electrode dislocation, skin allergy, postoperative xerostomia, dizziness, and arrhythmia.?;Additional dose of antiemetic within 48 hours post-surgery (e.g., additional tropisetron or metoclopramide);

Countries

China

Contacts

Public ContactYUN LIU

Peking University School and Hospital of Stomatology

docsusieliu@hotmail.com+8613426341446

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026