ponv
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1)Age = 18 years; 2) American Society of Anesthesiologists (ASA) physical status I-III; 3) Patients scheduled for partial or total thyroidectomy.
Exclusion criteria
Exclusion criteria: 1. Patients thyroid lateral cervical lymph node dissection surgery; 2. Patients with coagulation dysfunction; 3. Chronic pain patients requiring opioid therapy before or after surgery; 4. Patients with left ventricular ejection fraction <40%, second-degree or greater atrioventricular block, sick sinus syndrome, or severe bradycardia (heart rate (HR) <50 beats per minute); 5. Patients with obstructive sleep apnea syndrome; 6. Patients with epilepsy or epileptic seizures; 7. Pregnant or breastfeeding patients; 8. Patients allergic to the test drug; 9. Patients unwilling to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence rate of nausea and vomiting within 48 hours postoperative.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of PONV (Postoperative Nausea and Vomiting), antiemetic therapy;Overall VAS score (Visual Analogue Pain Scale, VAS), Analgesic drug therapy; | — |
Countries
China
Contacts
The First Affiliated Hospital of Shandong First Medical University (Shandong Provincial Qianfoshan Hospital)