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Based on the theory of "Yang density leads to stability", this study explores the mechanism by which the Fushen Xiezhuo Formula regulates mitochondrial metabolic reprogramming through the PI3K-AKT pathway in the treatment of chronic kidney disease.

Based on the theory of "Yang density leads to stability", this study explores the mechanism by which the Fushen Xiezhuo Formula regulates mitochondrial metabolic reprogramming through the PI3K-AKT pathway in the treatment of chronic kidney disease.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025002171
Enrollment
Unknown
Registered
2025-11-08
Start date
2025-04-13
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease

Interventions

Experimental group:Rejuvenation of kidney and turbidity prescription Western medicine basic treatment

Sponsors

Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Meeting the diagnostic criteria for chronic kidney disease; (2) Aged between 18 and 80 years; (3) Meeting the traditional Chinese medicine diagnostic criteria; (4) Patients with well-controlled anemia, infection, electrolytes, blood glucose, blood pressure, and blood lipid levels; (5) Those who have signed the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Patients with acute kidney disease; (2) Patients with severe underlying diseases (such as severe hematopoietic system diseases, severe liver disease, severe cardiovascular and cerebrovascular diseases, etc.); (3) Patients complicated with malignant tumors; (4) Pregnant or lactating women; (5) Patients with comorbid mental disorders; (6) Patients with incomplete clinical data.

Design outcomes

Primary

MeasureTime frame
Blood creatinine;eGFR;Traditional Chinese medicine syndrome scoring table;

Secondary

MeasureTime frame
Blood urea nitrogen;Blood uric acid;

Countries

China

Contacts

Public ContactShu Zhanjun

Xinjiang Medical University

shu5857872@163.com13079975309

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026