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Brain effect mechanism ointment rubbing on Post-stroke spasticity based on fMRI

Brain effect mechanism of Baimai ointment rubbing on Post-stroke spasticity based on fMRI

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025002165
Enrollment
Unknown
Registered
2025-11-08
Start date
2024-04-09
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke spasticity

Interventions

Control group:Routine rehabilitation
Healthy Control Group:No intervention

Sponsors

Zhejiang Rehabilitation Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Patients with cerebral hemorrhage and cerebral infarction for the first time or lacunar cerebral infarction without sequelae. Onset ranges from 2 weeks to 1 year; (2) Age 30~80 years old; (3) The Brunnstrom stage of the affected limb was stage II. and III; (4) Have not received formal TCM rehabilitation or modern rehabilitation before clinical trials; (5) The patient is conscious stable and has hand dysfunction; (6) Right hand (7) A form of consent signed by the patient or signed by an immediate family member.

Exclusion criteria

Exclusion criteria: (1) Mini-Mental Status Examination (MMSE) scale< 27 points; (2) Combined with sensory aphasia or mental disorders and other diseases; (3) Unable to cooperate with the examination and treatment of patients; (4) Patients with serious primary diseases such as heart liver kidney and hematopoietic system; (5) History of cognitive impairment neuropsychiatric disorder drug abuse and alcoholism; (6) Diseases or states with major organ failure cancer and other diseases or states that have an impact on the patient's quality of life that exceeds the limb dysfunction after stroke; (7) Significant limb damage such as: fractures severe arthritis etc. and trauma to the surface skin of the limbs; (8) Those who have received nerve block treatment such as botulinum toxin or alcohol within 3 months before the start of the trial; (9) Those who participated in other clinical studies 6 months before the trial.

Design outcomes

Primary

MeasureTime frame
Modified Ashoworth Scale;

Secondary

MeasureTime frame
Fugl-meyer Motor Function Scale;Amplitude of Low Frequency Fluctuations and regional homogeneity;

Countries

China

Contacts

Public ContactYubo Huang

Zhejiang Rehabilitation Medical Center

hyb9612@163.com18257160611

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026