Colorectal cancer
Conditions
Interventions
Experimental group (taVNS group):Receive standard perioperative care and active taVNS intervention.
Control group (placebo electrical stimulation group):receives standard perioperative care and sham electrical stimulation intervention
Standard Care Group (only receiving standard perioperative care):As the control group, they do not receive electrical stimulation.
Sponsors
Xuzhou City Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Age: 18-70 years old; preoperative pathological diagnosis of colon or rectal cancer and planned to undergo laparoscopic radical surgery; American Society of Anesthesiologists (ASA) classification I-III; understanding and agreement to participate in this study.
Exclusion criteria
Exclusion criteria: Individuals with severe cardiovascular diseases, mental disorders, or other conditions affecting the function of the autonomic nervous system; those who have used medications that may impact HRV, such as antidepressants or anxiolytics, within the past 3 months; individuals allergic to electrical stimulation or with skin injuries; and pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scale (VAS);Postoperative 48-hour opioid consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery Quality Scale;First passage of gas and stool;Inflammation biomarker levels;Heart Rate Variability ; | — |
Countries
China
Contacts
Public ContactHu Yongcan
Xuzhou City Hospital of Traditional Chinese Medicine Hospital
Outcome results
None listed