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Study on the mechanism of gut-lung axis in the treatment of severe pneumonia by a traditional Chinese medicine complex combined with fecal microbiota transplantation

Based on the holistic view of microecological balance, study the mechanism of the gut - lung axis in the treatment of severe pneumonia by fecal microbiota transplantation combined with the Yiqitongfu prescription

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025002140
Enrollment
Unknown
Registered
2025-11-08
Start date
2024-05-10
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe pneumonia

Interventions

Disease Treatment Group:Conventional anti-infection treatment + Yiqi Tongfu Decoction
Health Group:none
Blank control group:Routine anti-infective treatment

Sponsors

Wuhan Traditional Chinese Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients who must meet all of the following 5 criteria can be included in this study: 1. Have indications of respiratory tract infection. 2. Be aged 18 - 70 years old, regardless of gender. 3. The patient and their family members voluntarily participate in the clinical trial and sign the informed consent form.

Exclusion criteria

Exclusion criteria: Patients who meet one or more of the following criteria should be excluded: 1. Those who are using drugs that may affect the clinical observation of this trial or are participating in other clinical trials; 2. Those who, in the judgment of the investigator, are not suitable to participate in this study.

Design outcomes

Primary

MeasureTime frame
Evaluation of fatality rate and disability rate;The use intensity and course of antibiotics;The time and parameters of the ventilator;Delirium, depression, pain, nutritional scoring scale scores;

Secondary

MeasureTime frame
Microbiota assessment;Immune assessment;Metabolic assessment;Nutritional assessment;

Countries

China

Contacts

Public ContactZhou Fang

Wuhan Traditional Chinese Medicine Hospital

184320196@qq.com13476035187

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026