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Observation on the Therapeutic Effect of Sangxing Cough-relieving Granules on Cough Variant Asthma Caused by Dryness Injury to the Lung and Research on Its Mechanism of Action through the IL-17 Signaling Pathway

Observation on the Therapeutic Effect of Sangxing Cough-relieving Granules on Cough Variant Asthma Caused by Dryness Injury to the Lung and Research on Its Mechanism of Action through the IL-17 Signaling Pathway

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025002131
Enrollment
Unknown
Registered
2025-11-08
Start date
2025-04-13
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cough Variant Asthma

Interventions

Treatment group:Sangxingzhike granules+montelukast sodium tablets
Control group:Sangxingzhike granules Placebo+montelukast sodium tablets

Sponsors

Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Meets the Western medical diagnostic criteria for cough variant asthma; (2) Meets the diagnostic criteria for the TCM syndrome of dry pathogen invading the lung in cough; (3) Age range: 18 - 75 years old (including 18 years old, but excluding 75 years old), gender not restricted; (4) Voluntarily participate in this trial and sign a written informed consent form.

Exclusion criteria

Exclusion criteria: (1) Including fever, lung infection, acute pharyngitis, etc.; (2) Having other primary diseases in organs other than the lungs; (3) Cognitive impairment or mental abnormalities. (4) Pregnant or lactating women, or those allergic to this drug. (5) Patients who have recently taken drugs that may cause coughing, such as ACEI class antihypertensive drugs. (6) Those with poor compliance and who arbitrarily change the treatment plan.

Design outcomes

Primary

MeasureTime frame
Improvement rate of total efficacy score for TCM syndromes;

Secondary

MeasureTime frame
C-reactive protein;Liver function;Kidney function;TCM syndrome score;Cough symptom score;Visual analog score;Lycester cough Quality of Life Questionnaire;Cough severity score;lung function;blood routine examination;

Countries

China

Contacts

Public ContactLi Fengsen

Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine

Fengsen602@163.com+86 139 9998 0996

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026