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Randomized Controlled Clinical Study of Zhenggu Shui in the Treatment of Knee Osteoarthritis of Qi Stagnation and Blood Stasis Type

Randomized Controlled Clinical Study of Zhenggu Shui in the Treatment of Knee Osteoarthritis of Qi Stagnation and Blood Stasis Type

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025002129
Enrollment
Unknown
Registered
2025-11-08
Start date
2025-07-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis of Qi Stagnation and Blood Stasis Type

Interventions

Experimental group:Zhenggushui + conventional treatment

Sponsors

China-Japan Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 90 Years

Inclusion criteria

Inclusion criteria: (1) Age 50-90 years old; (2) Meet the diagnostic criteria for knee osteoarthritis and the criteria for qi stagnation and blood stasis syndrome in traditional Chinese medicine and the initial pain VAS score is greater than or equal to 4; (3) Patients who have not undergone knee surgery before have not undergone KOA-related treatment in the last month or have a washout period of at least two weeks after treatment; (4) Voluntarily sign the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Those who do not meet the above inclusion criteria; (2) Pregnant or lactating women and mentally ill patients with severe malnutrition or with serious damage to the digestive tract heart brain kidney and hematopoietic system; (3) Patients with other rheumatic diseases at the same time; (4) The swollen joints are accompanied by skin ulceration and allergies.

Design outcomes

Primary

MeasureTime frame
Pain VAS score;

Secondary

MeasureTime frame
WOMAC score;TCM pattern score;ESR ;Joint swelling score;CRP;

Countries

China

Contacts

Public ContactWeiping Kong

China-Japan Friendship Hospital

Kongweiping75@126.com13611038252

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026