Diabetic peripheral neuropathy
Conditions
Interventions
Intervention Group:Methylcobalamin + Electroacupuncture
Control Group:Methylcobalamin + Sham Needle
Sponsors
Beijing University of Chinese Medicine Oriental Hospital
Eligibility
Sex/Gender
All
Age
20 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Diagnosed with type 2 diabetes mellitus and meets the diagnostic criteria for diabetic peripheral neuropathy (DPN); (2) Receiving routine care for anti-hyperglycemic therapy with stable blood glucose control and glycated hemoglobin <8.5%; (3) Toronto Clinical Scoring System (TCSS) score =6 points; (4) Age between 20 and 75 years; (5) Normal understanding and communication abilities, able to cooperate with the study, and voluntarily signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with severe organic diseases such as heart, brain, liver, and kidney failure; patients with malignant tumors and mental illnesses; (2) Individuals who have experienced acute infections or acute complications of diabetes (diabetic ketoacidosis, hyperglycemic hyperosmolar state) within the past 3 months; (3) Patients with autoimmune system diseases; (4) Pregnant or breastfeeding women; (5) Individuals who have undergone acupuncture treatment within the past 6 months; (6) Participants in other clinical trials simultaneously; (7) Individuals who have taken methylcobalamin, epalrestat, or alpha-lipoic acid (used to treat diabetic peripheral neuropathy) within the past 4 weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Toronto Clinical Neuropathy Scoring Scale (TCSS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Nerve Conduction Velocity (NCV);Neuro Quantitative Sensory Examination;Quantitative Sensory Testing using Visual Analog Scale (VAS);Fasting Blood Glucose;glycated hemoglobin; | — |
Countries
China
Contacts
Public ContactYi Wenming
Beijing University of Chinese Medicine Oriental Hospital
Outcome results
None listed