Thin endometrium
Conditions
Interventions
Acupuncture plus PRP group:Acupuncture plus PRP
Sponsors
Sichuan Jinxin Xinan Women and Children's Hospital (Bisheng Campus)
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosis of thin endometrium: Transvaginal ultrasound shows endometrial thickness <7 mm, and the ideal thickness (=7 mm) is not achieved in at least two menstrual cycles. 2. Age range: 20-40 years old, female. 3. Infertility diagnosis: Consistent with the World Health Organization (WHO) diagnostic criteria for infertility, and planning to receive ART treatment (such as in vitro fertilization-embryo transfer, IVF-ET). 4. Normal hormone levels: Basal hormone levels (FSH, LH, E2) within normal ranges, without severe endocrine diseases. 5. Informed consent signed: Patients voluntarily participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Uterine cavity abnormalities: Severe intrauterine adhesions, endometrial polyps, uterine fibroids (affecting uterine cavity morphology), or other uterine cavity lesions. 2. Severe systemic diseases: Such as severe cardiovascular diseases, hepatic/renal insufficiency, immune system diseases, etc. 3. Infections or inflammations: Active acute or chronic reproductive system infections (e.g., pelvic inflammatory disease, active endometriosis). 4. Coagulation disorders: Bleeding tendency or ongoing anticoagulant therapy. 5. Malignant tumors: History of or current malignant tumors. 6. Mental illnesses: Severe mental disorders or inability to cooperate with treatment. 7. Allergy history: Allergy to PRP or acupuncture treatment. 8. Recent use of hormonal drugs: Use of hormonal drugs (e.g., estrogen, progesterone) within 3 months prior to study initiation. 9. Others: Other conditions deemed unsuitable for participation by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical pregnancy rate;Uterine Artery Pulsatility Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| endometrium thickness;Uterine Artery Resistance Index;Uterine Artery Systolic Peak Velocity/Diastolic End Velocity Ratio;Endometrial Vascularization Index;embryo implantation rate;Uterine Flow Index; | — |
Countries
China
Contacts
Public ContactZheng Xiaoyan
Sichuan Jinxin Xinan Women and Children's Hospital (Bisheng Campus)
Outcome results
None listed