sepsis
Conditions
Interventions
Elderly Healthy Control Group:none
Non-elderly Sepsis Group:none
Elderly Sepsis Group:none
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1)age=18 years 2)Patients diagnosed with sepsis according to the Guidelines for the emergency treatment of sepsis/septic shock in China (2018) were included in this study which with infection and Sequential Organ Failure Assessment (SOFA) score = 2
Exclusion criteria
Exclusion criteria: 1)patients with malignant tumors; 2)Patients with known immunodeficiency such as organ or bone marrow transplantation HIV infection or those who have taken immunosuppressants in the last 3 months; 3)Serious primary diseases of the hematologic system such as leukemiamyelodysplastic syndromes and idiopathic thrombocytopenic purpera etc. 4)Have severe liver or kidney dysfunction(defined as a SOFA score of =3 for liver or kidney) 5)Subjects who in the judgement of the investigator are not suitable for participation in the study. For example poor adherence lack of willingness to treat etc. 6)Have participated in other clinical investigators within the last 30 days; 7)Pregnant or lactating women; 8)Patients who did not sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Specialized pro-resolving mediators(SPMs);Collection of TCM syndromes in clinical practice; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood routine indicators;Coagulation indicators;Demographic information;Comorbidity;History of present illness;Plasma cytokines;Immunity-related indicators;Blood gas analysis;Abdominal CT; Vital signs;Inflammation-related indicators;Collection of follow-up data for endpoint indicators;Biochemistry; | — |
Countries
China
Contacts
Public ContactHuayang Cai
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed