Recurrent abortion
Conditions
Interventions
Control group:Dexmedetomidine tablets+Aspirin
Treatment group: Kidney tonifying and blood activating formula+Dexmedetomidine tablets+Aspirin
Sponsors
Yueyang integrated traditional Chinese and Western Medicine Hospital Affiliated to Shanghai University of traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) Married women aged = 20 and = 40 years old; (2) Meets the Western diagnostic criteria for recurrent miscarriage and the traditional Chinese medicine diagnostic criteria for kidney deficiency and blood stasis syndrome; (3) Gestational weeks<10 weeks and ultrasound shows intrauterine pregnancy (with clear presence of primitive heartbeats fetal heart buds etc.); (4) Understand and agree to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Chromosomal abnormalities in both spouses; Abnormal anatomy of the female reproductive organs (such as uterine fibroids mediastinal uterus bicornuate uterus cervical dysfunction etc.); Microbial infection factors (such as Toxoplasma gondii cytomegalovirus herpes simplex rubella virus chlamydia etc.); Female endocrine abnormalities (such as polycystic ovary syndrome hyperthyroidism or hypothyroidism etc.); Immune diseases (2) Both husband and wife showed significant abnormalities in liver and kidney function tests electrocardiograms chest X-rays and blood and urine routine examinations. (3) For those who have received relevant treatments in the past 3 months such as taking anticoagulant or fibrinolytic drugs the efficacy is difficult to determine. (4) Use anticoagulants such as low-molecular-weight heparin as well as traditional Chinese medicine and traditional Chinese patent medicines and simple preparations such as Zishen Yuntai Pill. (5) Have a history of allergies to the medication used for treatment. (6)Individuals who have participated or are currently participating in other clinical trials within the past month prior to enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pass rate at 12 weeks of gestation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Uterine artery hemodynamics;blood clotting;Platelet aggregation rate;Coagulation factors (V VII VIII IX);Family Support Self Assessment Scale;Traditional Chinese Medicine Syndrome Integral Evaluation;Hamilton Anxiety Scale;Fetal development testing; | — |
Countries
China
Contacts
Public Contactdongli
Yueyang integrated traditional Chinese and Western Medicine Hospital Affiliated to Shanghai University of traditional Chinese Medicine
Outcome results
None listed