prolonged disorders of consciousness due to brain injuries.
Conditions
Interventions
Treatment group:Right ear acupuncture point taVNS stimulation
Control group:Sham stimulation
Treatment group:Left ear acupuncture point taVNS stimulation
Sponsors
Zhejiang Rehabilitation Medical Center
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1)Meet the pDoC diagnostic criteria 2)Age > 18 years no gender restrictions and no upper age limit 3)No use of neurostimulant drugs within 48 hours prior to enrollment 4)No application of neuromuscular blocking agents within 24 hours prior to enrollment 5)No facial or ear pain no recent ear trauma no metal implants including cardiac pacemaker not pregnant 6)The patient's guardian (parents children) or authorized agent voluntarily signs the informed consent form
Exclusion criteria
Exclusion criteria: 1)History of personal or family epilepsy seizures history of cardiovascular diseases history of progressive neurological or mental disorders 2)Untreated brain edema 3)Presence of metal implants in the body 4)Unstable vital signs 5)Contraindications for EEG and near-infrared spectroscopy (NIRS) detection: such as skin lesions or infections in the head area during data collection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coma Recovery Scale-Revised; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting-state fNIRS;Resting-state EEG; | — |
Countries
China
Contacts
Public ContactJing Shan
Zhejiang Rehabilitation Medical Center
Outcome results
None listed