Heart failure
Conditions
Interventions
Control group:Guide-directed medication therapy includes diuresis, vasodilation, improvement of cardiac function, and regulation of neuroendocrine activity.
Treatment group:Guide-directed medication therapy includes diuresis, vasodilation, improvement of cardiac function, and regulation of neuroendocrine activity, combined with the traditional Chinese med
Sponsors
Taicang Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: The patient met the diagnostic criteria of heart failure, diuretic resistance, deficiency of both qi and Yin, and stagnation of blood stasis. Be over 18 years of age. They voluntarily participated in the study, signed the informed consent form, and had good compliance. They could cooperate with follow-up by telephone and other forms. No other medications that might interfere with the trial had been taken in the previous month.
Exclusion criteria
Exclusion criteria: Patients who cannot cooperate with oral decoction; Patients with end-stage tumor, liver and kidney failure; Patients who participated in other oral TCM decoction projects in the past one month; Patients with allergic constitution and allergy to the test drugs; Patients with psychiatric disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour urine volume; | — |
Secondary
| Measure | Time frame |
|---|---|
| N-terminal pro-B-type natriuretic peptide (NT-ProBNP);TCM syndrome score and efficacy evaluation;AVP;cAMP;PKA;Urinary aquaporin-2 (AQP2);24-hour diuretic dose;Quality of life assessment using the Minnesota Living with Heart Failure Questionnaire (MLHFQ);Liver function;Renal function; | — |
Countries
China
Contacts
Public ContactYunhu Chen
Taicang Hospital of Traditional Chinese Medicine
Outcome results
None listed