stroke
Conditions
Interventions
Acupuncture and iTBS Group:Acupuncture and iTBS and receive conventional rehabilitation therapy
iTBS Group:iTBS and receive conventional rehabilitation therapy
Acupuncture Group:Acupuncture and receive conventional rehabilitation therapy
Sponsors
The Second Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1:First-episode stroke that meets the diagnostic criteria of the WHO Stroke Guidelines and the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2014 (published in 2015), confirmed by cranial CT or MRI imaging scans; 2:Disease duration > 2 weeks and < 6 months; 3:Stable condition after stroke; 4:Aged 18–85 years; 5:Presence of motor dysfunction, with the Brunnstrom stage of the affected upper limb, hand, and lower limb being grade III or above and below grade V; 6:The patient or authorized representative has signed the informed consent form for this study, commits to abiding by the research procedures, and cooperates with the implementation of the entire research process.
Exclusion criteria
Exclusion criteria: 1:Complicated with disorders that affect assessment and treatment, such as disturbance of consciousness, mixed aphasia, or dementia (Mini-Mental State Examination [MMSE] score: < 17 for illiterate subjects, < 20 for subjects with primary school education, < 24 for subjects with junior high school education or above); 2:Excessive muscle tone (Ashworth scale grade III or above) and upper limb muscle strength < grade 2; 3:Complicated with major diseases such as dysfunction of important organs including liver, kidney, or heart; 4:History of conditions that affect motor dysfunction or severe joint diseases of the upper or lower limbs (e.g., tumor, fracture); 5:Implanted cardiac pacemaker or other intracranial metal medical devices; 6:Previous history of epileptic seizures; 7:Pregnant or lactating women; 8:Subjects with skull defect or history of cranioplasty; 9:Infection or damage to the scalp, upper limbs, or lower limbs;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Motor Function Assessment Lower Extremity Scale, FMA-LE;Wolf Motor Function Test, WMFT; | — |
Secondary
| Measure | Time frame |
|---|---|
| Holden;MEP;Modified Barthel Index, MBI;Ashworth;Action Research Arm Test, ARAT;Berg Balance;Stroke-specific Quality of Life scale, SS-QOL;Indicators Based on fNIRS: Functional Connectivity of Motor-Related Brain Regions in Resting State, and HbO? Concentration Activation in Motor Function Task State;Central Motor Conduction Time ,CMCT;Timed Up and Go Test,TUG;Fugl-Meyer Motor Function Assessment Upper Extremity Scale, FMA-UE; | — |
Countries
hina
Contacts
Public ContactZhang QIaojun
The Second Hospital, Xi'an Jiaotong University
Outcome results
None listed