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Effect of acupuncture on brain networks in chronic tic disorders

The effect of acupuncture on the brain network related to chronic tic disorders and its efficacy prediction

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001992
Enrollment
Unknown
Registered
2025-10-22
Start date
2024-04-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tic disorders in children

Interventions

Healthy control group:No intervention
Acupuncture Treatment Group:Filiform needle acupuncture at Baihui, Sishencong, Shenmen, Lügu, Taichong, and Zhaohai points.
Sham Acupuncture Group:Milli needles are not shallow punctures

Sponsors

Capital center for children's health Capital medical university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
7 Years to 14 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria for CTD patients: (1) Meet the above-mentioned CTD diagnosis criteria; (2) Age 7-14 years old; (3) No acupuncture, medication, psychological therapy, or behavioral intervention targeting TD in the past 3 months; (4) Voluntarily participate in this clinical study and sign the informed consent. Healthy subjects: 30 healthy subjects matched in age, physical development, and educational level. Inclusion criteria for healthy subjects: (1) Age 7-14 years old; (2) Confirmed as healthy through physical examination, with no significant organic or functional diseases; no history of tic disorders or other mental psychological diseases; (3) No contraindications for MRI examination; (4) Voluntarily participate in this study and sign the informed consent. Note: Must meet the above criteria and be matched with CTD patients in terms of age, gender, years of education, etc., to be included in this study.

Exclusion criteria

Exclusion criteria: (1) Tourette syndrome and transient tic disorder; (2) YGTSS score = 50 points; (3) History of intellectual disability, schizophrenia, obsessive-compulsive disorder, affective disorders, intellectual impairment, autism, etc.; (4) Severe heart, liver, or kidney diseases, hyperthyroidism; individuals with unstable vital signs; (5) Coagulation disorders or high risk of bleeding; (6) Skin allergies; (7) MRI contraindications: metal implants in the body, claustrophobia, etc.

Design outcomes

Primary

MeasureTime frame
Yale Comprehensive Tic Severity Scale;Functional Magnetic Resonance Imaging Assessment Metrics;

Secondary

MeasureTime frame
Child Behavior Scale;Children's Quality of Life Assessment Scale;

Countries

China

Contacts

Public ContactLvxiaoqin

Capital center for children's health Capital medical university

xiaoqinzaigj@sina.com15510283603

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026