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The Impact of Cervical Distraction and Rotation Manipulation on Stress Strain Displacement of Intracranial Contents and Delineation of Cerebral Function

The Impact of Cervical Distraction and Rotation Manipulation on Stress Strain Displacement of Intracranial Contents and Delineation of Cerebral Function

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025001991
Enrollment
Unknown
Registered
2025-10-22
Start date
2025-01-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cervical intervertebral disc herniation

Interventions

Patients with cervical disc herniation (CDH):Cervical Distraction and Rotation Manipulation
Patients with neck discomfort but without cervical disc herniation:Cervical Distraction and Rotation Manipulation

Sponsors

Shanghai Traditional Chinese Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients with cervical disc herniation: 1 Confirmed via imaging examination as having mild (MSU grading zone 1B) or moderate (MSU grading zone 2B) right-sided cervical disc herniation (Figure 1); 2 Aged 20–50 years; 3 No history of tumors, trauma, or surgery; 4 BMI <24 kg/m²; 5 Self-Rating Anxiety Scale (SAS) score <53 and Self-Rating Depression Scale (SDS) score <53; 6 No massage therapy, physical therapy, or similar treatments in the past month; 7 Agree to participate in the study and sign an informed consent form. (2) Patients with neck discomfort but no cervical disc herniation: 1) Confirmed via imaging examination to have no cervical disc herniation; 2) Aged 20–50 years; 3) No history of tumors, trauma, or surgery; 4) BMI <24 kg/m²; 5) Self-Rating Anxiety Scale (SAS) score <53 and Self-Rating Depression Scale (SDS) score <53; 6) No massage therapy, physical therapy, or similar treatments in the past month; 7) Agree to participate in the study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: Patients with cervical disc herniation (CDH): 1) Do not meet imaging diagnostic criteria for CDH or the herniation does not conform to MSU grading zones 1B or 2B; 2) Severe internal medical diseases (e.g. cardiovascular or cerebrovascular disorders); 3) History of head or spinal trauma; 4) History of head or spinal surgery; 5) Autoimmune or infectious diseases; 6) Pregnant or lactating women; 7) Claustrophobia or metal implants preventing completion of the examination; 8) Concomitant conditions such as tumors infections immune system disorders or poorly controlled diabetes hypertension or heart disease. (2) Patients with neck discomfort but without cervical disc herniation: 1 Severe internal medical diseases (e.g. cardiovascular or cerebrovascular disorders); 2 History of head or spinal trauma; 3 History of head or spinal surgery; 4 Autoimmune or infectious diseases; 5 Pregnant or lactating women; 6 Claustrophobia or metal implants preventing completion of the examination; 7 Concomitant conditions such as tumors infections immune system disorders or poorly controlled diabetes hypertension or heart disease.

Design outcomes

Primary

MeasureTime frame
Resting-state functional brain imaging using fMRI;

Secondary

MeasureTime frame
Stress, strain, and displacement of intracranial contents during the implementation of the manual technique;The variation in the distance between the proximal end of the medulla oblongata and the foramen magnum;

Countries

China

Contacts

Public ContactFan Xue

Shanghai Municipal Hospital of Traditional Chinese Medicine

625764742@qq.com+86 13501692702

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026