Skip to content

Rehabilitation Effects of Wrist-Ankle Acupuncture in Migraine Treatment and Its Peripheral Blood Mechanism

The rehabilitation effects of wrist-ankle acupuncture in migraine treatment and the mechanism of action on peripheral blood.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001963
Enrollment
Unknown
Registered
2025-10-22
Start date
2025-11-20
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine without aura

Interventions

Routine acupuncture group:Main acupoints: Baihui (GV20), Fengchi (GB20, bilateral), and Lüe Gu (GB8, bilateral). Use disposable sterile fine needles (: 0.25×40mm) for acupuncture. After insertion, per
Wrist-ankle acupuncture + routine acupuncture group:Select the bilateral Shang 3, Shang 4, and Shang 5 acupoints in the wrist region. Use single-use sterile thin needles (0.25×40mm) and rapidly insert

Sponsors

Affiliated Rehabilitation Hospital of Fujian University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: The content meets the diagnostic criteria for migraine without aura according to the third edition of the International Classification of Headache Disorders (ICHD-3), combined with previous research literature (JAMA Internal Medicine, 2017). 1) Age between 18 and 55 years, regardless of gender; 2) At least 1 year of migraine history, with the age at first onset less than 50 years; 3) Right-handed, with education duration =6 years; 4) At least 2 migraine episodes in the past 4 weeks, with monthly attack days <15 days; 5) VAS score between 3 and 7; 6) Able to complete a headache diary independently; 7) Signed informed consent.

Exclusion criteria

Exclusion criteria: 1) Patients with a history of head trauma, secondary headaches, tension-type headaches, intermittent headaches, cluster headaches, and cardiovascular and digestive system diseases; 2) Those who have undergone major intestinal resection or large gastrointestinal surgery in the past; 3) Individuals with mental illness, infections, bleeding disorders, or allergic constitutions; 4) Pregnant women, breastfeeding women, or those planning to become pregnant within the next 6 months; 5) Those unable to understand or record headache diaries; 6) Presence of contraindications for MRI; 7) Use of antibiotics or acupuncture treatment within the past 3 months, lasting 3 days or more; 8) Long-term use of pain medications and drugs for migraine prevention; 9) Participation in similar studies within the past 3 months.

Design outcomes

Primary

MeasureTime frame
Number of days with headache attacks;headache attack frequency;Headache Duration;Visual Analog Scale (VAS);

Secondary

MeasureTime frame
Migraine-Specific Quality of Life Questionnaire (MSQ);Self-Rating Anxiety Scale (SAS);Self-Rating Depression Scale (SDS);Pittsburgh Sleep Quality Index (PSQI);

Countries

China

Contacts

Public ContactYu Xiangmei

Fujian University of Traditional Chinese Medicine Affiliated Hospital of Rehabilitation, Fujian University of Traditional Chinese Medicine

yxmtcm@163.com13405942802

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026