Cardiogenic Shock
Conditions
Interventions
Control group:The diagnosis and treatment are carried out in accordance with the "Chinese Expert Consensus on the Diagnosis and Treatment of Cardiogenic Shock (2018)" and the latest guidelines, ensuri
Pogejiuxin Decoction Group:Conventional Western medical treatment + Pogejiuxin Decoction (Prepared Aconite Root 30 g,D ried Ginger 20 g,Asiatic Cornelian Cherry Fruit (Cornus officinalis) 20 g,Honey-f
Sponsors
Emergency Department, University Town, Guangdong Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) At the time of screening, the age should be =18 years old and =80 years old, with no gender restrictions. 2) A patient diagnosed with cardiogenic shock (CS); 3) Willing to participate in this study and have the informed consent form signed by the subject or their legal representative;
Exclusion criteria
Exclusion criteria: 1)Patients with severe diseases of the respiratory system (such as severe pulmonary insufficiency, pulmonary embolism, etc.) or endocrine diseases, malignant tumors, active gastrointestinal bleeding, blood disorders, etc. 2) Those with any of the following conditions: severe liver dysfunction (ALT or AST exceeding the upper limit of normal by more than three times due to non-heart diseases), decompensated liver cirrhosis, or severe renal insufficiency (eGFR<15ml/min); Patients with known immune deficiencies, such as those who have received organ or bone marrow transplants, have HIV infection, or have taken immunosuppressants in the past three months; 3) Those with severe allergic or non-allergic drug reactions, or a history of allergy to two or more drugs, or those known to possibly be allergic to or have serious adverse reactions to the drugs under study; 4) Pregnant and lactating women; 5) Other matters that the researcher deems unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical treatment effective rate;Cardiac function indicators (CO, LVESV, LVEF, LVEDD, FS);BNP;6-minute walk test;TCM syndrome scoring;Mechanical assistance time, vasoactive drug time;The rehospitalization rate, MACE events and mortality rate within one year of follow-up;Incidence of adverse reactions; | — |
Countries
China
Contacts
Public ContactZhuang Jieqin
Emergency Department, University Town, Guangdong Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed