varicocele
Conditions
Interventions
observation group:Tengxi formula
control group:Aescuven forte
Sponsors
xiyuan hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Meet the Western medical diagnostic criteria for VC; (2) Meet the Chinese medicine diagnostic criteria of essence chamber stasis and heat syndrome; (3) The patient's age is between 18 and 60 years old; (4) Those who have not had VC surgery; (5) Voluntarily participated in this study and signed an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Secondary varicocele, including those caused by nutcracker syndrome, compression by abdominal or retroperitoneal tumors, etc.; (2) Patients with inflammation, tuberculosis or tumors in accessory gonads such as the prostate, epididymis, and testicles; (3) Diseases such as testicular hydrocele and filarial spermatic cord lymphangitis; (4) Acute or chronic scrotal eczema, with symptoms such as redness, swelling, blisters, exudation, and local lichenification of the scrotal skin; (5) Patients with severe primary diseases, including but not limited to severe diarrhea, uncontrolled cardiovascular and cerebrovascular diseases (such as unstable angina pectoris, severe arrhythmia, acute stroke, etc.), decompensated liver disease (ALT/AST > 1.5 times the upper limit of normal), severe renal insufficiency (serum creatinine > upper limit of normal), uncontrolled malignant tumors, active immune system diseases, hematological system diseases (such as severe anemia, coagulation disorders), and other diseases that the observer deems may affect the safety of observation; (6) Patients with severe mental and psychological diseases (such as schizophrenia, severe depression, anxiety disorder, etc.) that are not effectively controlled, or those who need to take drugs that may affect the accuracy of autonomous symptom reporting for a long time (such as potent sedatives); (7) Patients with oligozoospermia or asthenozoospermia, or those who have plans to prepare for pregnancy within the past 3 months; (8) Having participated in other clinical trials or used drugs that affect VC or coagulation function within the past 3 months; (9) Patients who are currently taking Aescuven forte regularly due to other concurrent diseases, or those who have used Aescuven forte within the past 1 month; (10) Patients with allergic constitution, a history of allergy to the ingredients of this product, or those who cannot tolerate the drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analogue scale score; | — |
Secondary
| Measure | Time frame |
|---|---|
| spermatic vein diameter;duration of reflux;Traditional Chinese Medicine syndrome score; | — |
Countries
China
Contacts
Public ContactFu Wang
xiyuan hospital of China Academy of Chinese Medical Sciences
Outcome results
None listed