Labor pain
Conditions
Interventions
Control group:no invasive analgesic procedure
Combined spinal-epidural anesthesia group:Combined spinal-epidural anesthesia for labor analgesia.
Acupoint catgut embedding group:Acupoint catgut embedding for analgesia
Acupoint catgut embedding combined with combined spinal-epidural anesthesia group:Acupoint catgut embedding combined with combined spinal-epidural anesthesia for labor analgesia
Sponsors
The Third Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) Nulliparous singleton pregnancy with cephalic presentation; (2) Term pregnancy with spontaneous onset of labor and cervical dilation of 2 cm; (3) No contraindications for acupoint catgut embedding, combined spinal-epidural anesthesia, and vaginal delivery; (4) Voluntarily participate in the study.
Exclusion criteria
Exclusion criteria: (1) Any maternal and fetal complications, such as metabolic disease, immunologic diseases, hypertensive disorders, premature rupture of membranes, fetal growth restriction and amniotic fluid disorders; (2) Contraindications for ACE (including bleeding tendency, skin infection, ulceration, and allergic constitution), CSEA, or vaginal delivery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale/Score, VAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dosage of anesthetic drugs;The duration of labor and the mode of delivery;Prognosis of newborns;Interleukin-1 beta;Tumor Necrosis Factor-alpha;Interleukin-10;Prostaglandin E2;The ultrastructure of villous trophoblast cells; | — |
Countries
China
Contacts
Public ContactWu Lingling
The Third Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed