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Association Study on Traditional Chinese Medicine Syndrome Characteristics and Fundus Changes in Chronic Kidney Disease

Association Study on Traditional Chinese Medicine Syndrome Characteristics and Fundus Changes in Chronic Kidney Disease

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ITMCTR
Registry ID
ITMCTR2025001912
Enrollment
Unknown
Registered
2025-10-15
Start date
2025-09-01
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Disease

Interventions

Observation group-Diabetic nephropathy group:No
Observation group-Idiopathic Membranous Nephropathy group:No
Observation group-IgA nephropathy group:No
Observation group-Minimal Change Disease group:No
Observation group-Hypertensive Renal Disease group:No
Observation group-Lupus Nephritis group:No

Sponsors

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) The subjects signed the informed consent form and cooperated with the research; (2) The subjects were aged between 18 and 80 years old; (3) The subjects who met the diagnostic criteria for chronic kidney disease, underwent renal biopsy to determine the type of kidney disease, and whose pathological diagnosis was based on the "Expert Consensus on Standardized Diagnosis of Renal Biopsy Pathology"; (4) The subjects underwent optical coherence tomography imaging and fundus photography to clarify the fundus manifestations; (5) The subjects had complete clinical data and were able to cooperate to complete this study

Exclusion criteria

Exclusion criteria: (1) Patients with unstable conditions and those with other severe systemic diseases, such as heart failure, liver failure, malignant tumors, and severe infectious diseases; (2) Patients undergoing renal replacement therapy such as hemodialysis, plasma exchange, hemofiltration, peritoneal dialysis, or kidney transplantation, or those who have undergone such therapy within the past 3 months; (3) Patients who cannot fix their gaze during ophthalmological examinations, or whose mental state cannot cooperate with observation; (4) Pregnant or lactating women; (5) Patients with multiple syndromes in traditional Chinese medicine diagnosis, without prioritizing any one, or with complex syndromes; (6) Patients with other severe eye diseases, such as glaucoma, retinal vein occlusion, optic neuritis, etc., or those whose other eye disorders affect the retina; (7) Patients judged by the researchers to have other unsuitable conditions for inclusion; (8) Patients participating in other clinical studies; Note: The inclusion and exclusion criteria for eye diseases in this study refer to each eye separately. That is, as long as one eye of the patient meets the inclusion criteria and this eye does not fall under the exclusion criteria, that eye can be included. If both eyes meet the criteria, the right eye will be included.

Design outcomes

Primary

MeasureTime frame
Optical coherence tomography imaging;Information on TCM Syndromes;

Countries

China

Contacts

Public ContactChen Jiang

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

jiangchen_doctor@163.com18622662919

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026