migraine
Conditions
Interventions
treatment group:Qingqiao Congming Decoction
control group:placebo
Sponsors
Gansu Provincial Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Age range: 18 - 65 years old, gender not restricted; 2) Meets the diagnostic criteria for migraine as defined in the "International Classification of Headache Disorders Version 3" (ICHD-3) (including either a migraine without aura or with aura); average weekly headache duration (converted) is = 1 day and = 4 days. 3) Voluntarily participates in this study, signs the informed consent form, has good compliance, and can be followed up on time; 4) Has not received any other systemic preventive treatment for migraine in the past 1 month.
Exclusion criteria
Exclusion criteria: 1) Pregnant women, lactating women or those with a pregnancy plan within the past six months; 2) Those with secondary headaches (such as tumors, brain trauma, infections, etc.); 3) Patients who have used migraine prevention drugs (such as CGRP monoclonal antibodies) within the past month; 4) With abnormal laboratory indicators (ALT/AST > 1.5 times the upper limit, eGFR < 60 ml/min); 5) Patients with organic lesions in important organs such as the heart, lungs, liver, and kidneys, or those with mental disorders and other reasons that prevent them from cooperating with the trial; 6) Those allergic to the test drugs and their excipients; 7) Those undergoing other treatments or participating in other clinical research studies; 8) Those judged by the researchers to be unsuitable for inclusion in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of migraine attacks (average per week) changes;Duration of migraine (hours) variation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in headache intensity (VAS score);Traditional Chinese medicine syndrome scoring (including the nature of headache, tongue appearance, pulse characteristics, etc.);Migraine Impact Scale (MSQ);HIT-6 score;Migraine Disability Assessment;Anxiety/Depression Assessment; | — |
Countries
China
Contacts
Public ContactZhang Zhiming
Gansu Provincial Hospital of Traditional Chinese Medicine
Outcome results
None listed