chloasma
Conditions
Interventions
control group:Oral Vitamin C+E
Observers:Oral administration of vitamin C+E and Sanhuang Zengmian Tang with modifications
Sponsors
Affiliated Hospital of Chengdu University of Traditional Chinese Medicine (Sichuan Provincial Hospital of Traditional Chinese Medicine)
Eligibility
Sex/Gender
All
Age
25 Years to 55 Years
Inclusion criteria
Inclusion criteria: (1) Meets the diagnostic criteria of traditional Chinese and Western medicine; (2) The age range is between 25 and 55 years old, and no relevant treatment was received within one month before the visit; (3) Complete and reliable clinical case data; (4) Those who voluntarily sign an informed consent form, are able to cooperate with treatment, and can be followed up.
Exclusion criteria
Exclusion criteria: (1) In the period of preparing for pregnancy, pregnancy, or lactation; (2) Patients with severe primary diseases of various organ systems, endocrine system diseases, malignant tumors, mental illnesses, hematopoietic system diseases or thrombophilia tendencies, and previous allergies; (3) Individuals who have received local cosmetic treatment at the test site within 6 months prior to the start of the study; (4) Those who cannot avoid direct sunlight exposure; (5) Those who cannot take medication and follow up according to regulations, cannot judge the efficacy, or have incomplete data that affects the assessment of efficacy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Enzyme linked immunosorbent assay (ELISA) was used to measure the levels of SOD and MDA in the serum of patients; | — |
Secondary
| Measure | Time frame |
|---|---|
| OLINK targeted proteomics technology is used to detect the protein expression of SCF, c-kit, MAPK, MITF, and TYR, factors related to the SCF/c-kit/MAPK pathway.;General Treatment Completion Evaluation Scale;Melasma Severity Index (MASI) score;Skin imaging evaluation;Traditional Chinese Medicine Syndrome Score; | — |
Countries
China
Contacts
Public Contactwujingping
Affiliated Hospital of Chengdu University of Traditional Chinese Medicine
Outcome results
None listed