Radiation Induced Oral Mucositis
Conditions
Interventions
Treatment group 1:Radiotherapy plus QiHuQingJie Decotion No. 1
Treatment group 2:Radiotherapy plus QiHuQingJie Decotion No. 2
Sponsors
The affiliated hospital of Hunan Academy of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Patients with malignant head and neck tumors undergoing radiotherapy or chemoradiotherapy. Radiotherapy dose = 50 Gy. Expected survival of more than 3 months. The subject has a relatively good physical condition with a Karnofsky Performance Status (KPS) score = 70. Age = 18 years. Before radiotherapy peripheral blood leukocytes = 3.0×10^9/L; neutrophils = 1.5×10^9/L; hemoglobin = 90 g/L; platelets = 75×10^9/L.
Exclusion criteria
Exclusion criteria: Failure to meet the inclusion criteria. Pregnant or breastfeeding women. Patients with mental illness. Individuals with an allergic constitution or known allergies to traditional Chinese medicine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RTOG Classification criteria for acute radiation injury;Radiotherapy completion rate;Incidence of radiation-induced oral mucositis; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS score;Karnofsky Performance Status;Weight;TCM symptom score; | — |
Countries
China
Contacts
Public ContactPeng Yan-mei
Hunan Academy of Chinese Medicine
Outcome results
None listed