Helicobacter pylori
Conditions
Interventions
Western Medicine Group:Standard quadruple therapy course of treatment 2 weeks.
Huoxiang Anwei Granules Group:Administer Huoxiang Anwei Granules 1 bag/time 2 times/day in combination with standard quadruple therapy for a course of 2 weeks.
Huoxiang Anwei Powder Group:Administer Huoxiang Anwei San 1 dose/day in combination with standard quadruple therapy for a course of 2 weeks.
Sponsors
Shenzhen Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for refractory H. pylori infection; (2) Aged between 18 and 65; (3) Volunteer to undergo the trial, gastroscopy, HP resistance and drug sensitivity testing, and sign the informed consent form; (4) Normal cognitive function, without reading and writing ability impairment; able to actively cooperate and participate in research and investigation.
Exclusion criteria
Exclusion criteria: (1) Patients with severe lesions in major organs such as liver liver and kidneys hematopoietic system diseases and tumors; (2) Used antibiotics acid suppressants and bismuth supplements within 4 weeks prior to treatment; (3) Systemic diseases that affect digestive tract dynamics (such as hyperthyroidism diabetes chronic renal insufficiency mental and nervous system diseases etc.); (4) History of upper gastrointestinal bleeding partial gastrectomy severe gastric mucosal atrophy/intestinal metaplasia etc; (5) Pregnant or breastfeeding women who are preparing for pregnancy; (6) Individuals with a history of allergies to the drugs used in this study; (7) Patients with severe primary and mental illnesses; (8) Subjects currently participating in other clinical trials; (9) The screening period test results indicate that ALT and AST values exceed the upper limit of the normal range by 2 times and total bilirubin and BUN values exceed the upper limit of the normal range by 1.5 times.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 13 C-urea breath test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement of TCM symptoms;Improvement in quality of life;Degree of relief of anxiety and depression; | — |
Countries
China
Contacts
Public ContactShaoju Guo
SHENZHEN Traditional Chinese Medicine Hospital
Outcome results
None listed