Obesity
Conditions
Interventions
True STIM group:Scalp acupuncture at the Stomach and Gallbladder Meridians. The electroacupuncture device delivered an actual output current of 1-2 mA, administered three times per week for 20 minutes
Sham STIM group:Patch electrodes were placed at the same acupoints with zero current output, while maintaining identical operation frequency and session duration as the True STIM group.
Sponsors
Huanghe College of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Demographic characteristics: Aged 18–60 years, regardless of gender. 2.Obesity diagnosis: BMI =28 kg/m² (mean of three measurements), or BMI =25 kg/m² combined with at least one metabolic abnormality:Fasting plasma glucose (FPG) =5.6 mmol/L;Triglycerides (TG) =1.7 mmol/L;High-density lipoprotein cholesterol (HDL-C) <1.0 mmol/L (male) or <1.3 mmol/L (female).
Exclusion criteria
Exclusion criteria: 1.Pregnancy or lactation. 2.Severe cardiovascular or cerebrovascular diseases (e.g., heart failure, history of stroke) or implanted electronic devices (e.g., cardiac pacemakers). 3.History of bariatric surgery or use of weight-loss medications (such as GLP-1 receptor agonists or orlistat) within the past 3 months. 4.Thyroid dysfunction (TSH beyond ±20% of the normal range). 5.Hepatic or renal insufficiency (ALT/AST >3× upper limit of normal; eGFR <60 mL/min/1.73m²). 6.Psychiatric disorders or inability to cooperate with evaluations (e.g., major depression, cognitive impairment).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body weight;visceral fat area (VFA);serum total bile acid (TBA); | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting Plasma Glucose(FPG);Homeostatic Model Assessment of Insulin Resistance(HOMA-IR);Fibroblast Growth Factor 19 (FGF19 );Hunger Score;Incidence of Adverse Events; | — |
Countries
China
Contacts
Public ContactYaxia Yan
Huanghe College of Science and Technology
Outcome results
None listed