Asymptomatic Hyperuricemia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Patients who meet the diagnostic criteria for asymptomatic hyperuricemia as defined by the Integrated Traditional Chinese and Western Medicine Guidelines for the Diagnosis and Treatment of Gout and Hyperuricemia (2023), which was proposed by the Chinese Society of Integrated Traditional Chinese and Western Medicine and drafted by the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine; (2) Patients with obesity, defined as a body mass index (BMI) = 25 kg/m²; (3) Patients aged between 18 and 70 years; (4) Patients who voluntarily agree to participate in this study, undergo relevant examinations and treatments, and provide written informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients with a previous history of gout; (2) Patients with poorly controlled type 2 diabetes (HbA1c = 8.4%) or hypertension [SBP = 160 mmHg or DBP = 100 mmHg] that may affect uric acid excretion; (3) Patients with comorbid life-threatening cardiovascular or cerebrovascular diseases, or severe hepatic or renal impairment [chronic kidney disease (CKD) stage = 2, or serum creatinine, blood urea nitrogen, alanine aminotransferase (ALT), or aspartate aminotransferase (AST) levels exceeding twice the upper limit of normal]; (4) Patients with alcohol abuse, pregnancy, lactation, or psychiatric disorders; (5) Patients with a history of severe allergies; (6) Patients who have used medications affecting uric acid metabolism within the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of patients with uric acid (UA) reaching target levels; | — |
Secondary
| Measure | Time frame |
|---|---|
| Uric Acid (SUA) Changes;Uric Acid (BUA) Target Achievement Rate?;Lipid Profile;Fasting Blood Glucose;Liver Function;Renal Function;Body Weight,Body Mass Index;Waist Circumference ,Hip Circumference;Blood Pressure; | — |
Countries
China
Contacts
Puyang Hospital of Traditional Chinese Medicine