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Efficacy and Safety of Moxibustion for Asymptomatic Hyperuricemia with Obesity: A Randomized Controlled Clinical Trial

Efficacy and Safety of Moxibustion for Asymptomatic Hyperuricemia with Obesity: A Randomized Controlled Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001858
Enrollment
Unknown
Registered
2025-09-26
Start date
2025-10-08
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asymptomatic Hyperuricemia

Interventions

True Moxibustion Group:The patient was instructed to lie supine. After local disinfection of the acupoints, the moxa stick fixed on the moxibustion stand was positioned 3–5 cm above the surface of the
Sham Moxibustion Group:The same type of moxa stick was ignited but fixed 8–10 cm above the skin surface at the acupoint, maintaining the temperature at 37 ± 1 °C. Each moxibustion session lasted 30 mi

Sponsors

Puyang Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Patients who meet the diagnostic criteria for asymptomatic hyperuricemia as defined by the Integrated Traditional Chinese and Western Medicine Guidelines for the Diagnosis and Treatment of Gout and Hyperuricemia (2023), which was proposed by the Chinese Society of Integrated Traditional Chinese and Western Medicine and drafted by the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine; (2) Patients with obesity, defined as a body mass index (BMI) = 25 kg/m²; (3) Patients aged between 18 and 70 years; (4) Patients who voluntarily agree to participate in this study, undergo relevant examinations and treatments, and provide written informed consent.

Exclusion criteria

Exclusion criteria: (1) Patients with a previous history of gout; (2) Patients with poorly controlled type 2 diabetes (HbA1c = 8.4%) or hypertension [SBP = 160 mmHg or DBP = 100 mmHg] that may affect uric acid excretion; (3) Patients with comorbid life-threatening cardiovascular or cerebrovascular diseases, or severe hepatic or renal impairment [chronic kidney disease (CKD) stage = 2, or serum creatinine, blood urea nitrogen, alanine aminotransferase (ALT), or aspartate aminotransferase (AST) levels exceeding twice the upper limit of normal]; (4) Patients with alcohol abuse, pregnancy, lactation, or psychiatric disorders; (5) Patients with a history of severe allergies; (6) Patients who have used medications affecting uric acid metabolism within the past three months.

Design outcomes

Primary

MeasureTime frame
Number of patients with uric acid (UA) reaching target levels;

Secondary

MeasureTime frame
Uric Acid (SUA) Changes;Uric Acid (BUA) Target Achievement Rate?;Lipid Profile;Fasting Blood Glucose;Liver Function;Renal Function;Body Weight,Body Mass Index;Waist Circumference ,Hip Circumference;Blood Pressure;

Countries

China

Contacts

Public ContactWei Huina

Puyang Hospital of Traditional Chinese Medicine

13213916253@163.com13213916253

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026