Recurrent spontaneous abortion
Conditions
Interventions
The group for strengthening the kidney and stabilizing the fetus:Dydrogesterone tablets 10mg each time, twice a day
Traditional Chinese medicine for strengthening the kidney and stabilizing the fetus, take 150ml each time, three times a day
Western Medicine treatment group:Dydrogesterone tablets 10mg each time, twice a day
Healthy Pregnancy Group:No intervention was carried out
only relevant clinical data collection was conducted
Sponsors
Affiliated Hospital of Chengdu University of TCM
Eligibility
Sex/Gender
Female
Age
22 Years to 49 Years
Inclusion criteria
Inclusion criteria: (1) Meeting the diagnostic criteria of Western medicine and the syndrome differentiation standards of Traditional Chinese Medicine; (2) Having experienced two or more spontaneous abortions; (3) Gestational age less than 12 weeks; (4) No abnormal semen in the husband; (5) No chromosomal abnormalities in both the husband and wife; (6) No anatomical structural abnormalities; (7) No autoimmune diseases; (8) No endocrine disorders; (9) No infectious factors; (10) No abnormalities in blood coagulation analysis; (11) The subjects have given informed consent and voluntarily signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Genital tract malformations; (2) Acute or chronic infection period; (3) Abnormal semen in the male partner; (4) Autoimmune diseases; (5) Recent use of immunosuppressants; (6) Coexisting diabetes, hypertension, heart disease, liver and kidney diseases, and blood disorders; (7) History of smoking and excessive drinking; (8) Vaccination within the last three months; (9) Failure to take medication as prescribed, making it impossible to assess the therapeutic effect, or incomplete data affecting the assessment of the therapeutic effect.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical signs and symptoms;Metabolomics; | — |
Secondary
| Measure | Time frame |
|---|---|
| The insertion time for stabilizing the fetus;Gynecological examination;Gynecological color Doppler ultrasound examination;Estrogen;Progesterone;Human chorionic gonadotropin; | — |
Countries
China
Contacts
Public ContactLinwen Deng
Affiliated Hospital of Chengdu University of TCM
Outcome results
None listed