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Effects and Neural Mechanisms of Tongdu Tiaoshen Acupuncture on Post-stroke Mild Cognitive Impairment (PSMCI): An fNIRS Study

Effects and Neural Mechanisms of Tongdu Tiaoshen Acupuncture on Post-stroke Mild Cognitive Impairment (PSMCI): An fNIRS Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001848
Enrollment
Unknown
Registered
2025-09-26
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke Mild Cognitive Impairment

Interventions

Control Group A:no
Experimental Group:Tongdu Tiaoshen Acupuncture
Control Group B:sham-acupuncture

Sponsors

Guangdong Provincial Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria for Post-Stroke Mild Cognitive Impairment (i.e., Experimental Group and Control Group B): 1) Meet diagnostic criteria for "stroke" and mild cognitive impairment; 2) Cognitive impairment occurs within 1 to 6 months after stroke, demonstrating a clear temporal relationship; 3) MMSE scores: =17 for no formal education, =20 for primary education, =24 for secondary education or above; MoCA score <26; 4) Age between 30 and 70 years; 5) Conscious with stable vital signs; 6) Ability to cooperate with rehabilitation assessments and acupuncture treatment; 7) No participation in other interventional studies within 1 month prior to enrollment. Inclusion Criteria for Post-Stroke Non-Mild Cognitive Impairment (i.e., Control Group A): 1) Meet diagnostic criteria for "stroke"; 2) Within 1 to 6 months after stroke; 3) Absence of cognitive impairment, with MoCA score =26; 4) Age between 30 and 70 years; 5) Conscious with stable vital signs; 6) Ability to cooperate with rehabilitation assessments; 7) No participation in other interventional studies within 1 month prior to enrollment.

Exclusion criteria

Exclusion criteria: Exclusion Criteria (Applicable to Experimental Group, Control Group A, and Control Group B): 1) Cognitive impairment caused by vascular dementia, Alzheimer's disease, Parkinson's disease, or other neurological disorders; 2) Pre-existing cognitive domain impairment prior to the onset of stroke; 3) History of psychiatric disorders, drug abuse, or alcohol addiction; 4) Pregnancy or lactation; 5) Patients with skin lesions or dermatological conditions at proposed acupuncture sites.

Design outcomes

Primary

MeasureTime frame
cognitive function ;cognitive function ;

Secondary

MeasureTime frame
depression;anxiety;ADL;motor function ;Brain function network;

Countries

China

Contacts

Public ContactZhan Jie

Guangdong Provincial Hospital of Chinese Medicine

zhanjie34@126.com15818136908

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026