Asymptomatic Hyperuricemia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Participants must meet all of the following criteria: 1.Diagnostic Confirmation Fulfill the diagnostic criteria for asymptomatic hyperuricemia as defined in the 2023 Integrated Traditional Chinese and Western Medicine Guidelines for the Diagnosis and Treatment of Gout and Hyperuricemia Issued by:Chinese Society of Integrated Traditional and Western Medicine Drafted by:First Teaching Hospital of Tianjin University of Traditional Chinese Medicine 2.Age Range 18 to 70 years old (inclusive) 3. Informed Consent Voluntarily agree to participate in the study Willing to undergo all required examinations and treatments Provide written informed consent
Exclusion criteria
Exclusion criteria: Participants will be excluded if they meet any of the following conditions: 1. Gout History Previous diagnosis of gout (acute or chronic) 2. Poorly Controlled Comorbidities Type 2 diabetes with HbA1c =8.4% Uncontrolled hypertension )SBP =160 mmHg or DBP =100 mmHg) Other conditions known to disrupt uric acid metabolism 3. Organ Dysfunction Cardiovascular or cerebrovascular diseases with life-threatening risks Severe hepatic/renal impairment: Chronic kidney disease (CKD stage =2) Serum creatinine BUN ALT or AST levels >2× upper limit of normal 4. Special Populations Alcohol dependence (defined as >40 g/day ethanol for men >20 g/day for women) Pregnancy or lactation Psychiatric disorders 5. Hypersensitivity History of severe allergic reactions 6. Medication Interference Use of urate-altering drugs (e.g. allopurinol febuxostat probenecid) within 3 months prior
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of patients with blood uric acid (UA) reaching target levels; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum Uric Acid (SUA) Changes;Blood Uric Acid (BUA) Target Achievement Rate?;Lipid Profile;Fasting Blood Glucose;Liver Function;Renal Function;Body Weight,Body Mass Index;Waist Circumference ,Hip Circumference;Blood Pressure; | — |
Countries
China
Contacts
Puyang Hospital of Traditional Chinese Medicine