Sepsis-associated encephalopathy
Conditions
Interventions
control group :Standard Western medical treatment + drinking water
treatment group :Standard Western medical treatment + Modified Shengtie Luo Decoction
Sponsors
Shanghai Yueyang Integrated Traditional Chinese Medicine and Western Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1: Age = 18 years and = 80 years gender unrestricted; 2: Conforming to the diagnostic criteria of phlegm-fire disturbing the upper body in traditional Chinese medicine; 3: Meet the Western medical diagnostic criteria for sepsis-associated encephalopathy; 4: Met the criteria for consciousness disorder (CAM-ICU positive); 5: The patient or the legal representative understands agrees to participate in this study and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1: Patients with severe underlying diseases such as malignant tumors (non-stable stage) liver cirrhosis chronic renal failure (uremic stage) hematological diseases and HIV; 2: Patients with a SOFA score of =15 or organ dysfunction with a single SOFA score of =4 or an Acute Physiology and Chronic Health Evaluation II (APACHE II) score of =30 or those who refuse active treatment; 3: Patients with endotracheal intubation; 4: Patients with drug allergies in this study; 5: Patients who are pregnant or lactating; 6: Those who have participated in other drug clinical trials within 3 months prior to the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delirium Rating Scale - Revised 98 (DRS-R98) score ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Biomarkers of nerve injury ;SOFA score ;RASS score ;Systemic inflammatory markers ;Glasgow Coma Scale score ;TCM syndrome score ;APACHE II score ;inflammatory factor ;Duration of use of restraint belts; | — |
Countries
China
Contacts
Public ContactQianYiMing
Shanghai Yueyang Integrated Traditional Chinese Medicine and Western Medicine Hospital
Outcome results
None listed