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Exploring the Mechanism of He-Mu Point Combination Acupuncture in Improving Post-Stroke Cognitive Impairment Based on Functional Near-Infrared Spectroscopy (fNIRS) and the Brain-Gut Axis

Exploring the Mechanism of He-Mu Point Combination Acupuncture in Improving Post-Stroke Cognitive Impairment Based on Functional Near-Infrared Spectroscopy (fNIRS) and the Brain-Gut Axis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001771
Enrollment
Unknown
Registered
2025-09-18
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Control Group:Basic Rehabilitation Therapy + Routine Acupuncture
Experimental Group:Basic Rehabilitation Therapy + Routine Acupuncture+He-Mu Point Combination Acupuncture

Sponsors

The Xiangya Hospital of Central South University, Jiangxi Branch
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) In line with the diagnostic criteria for "acute ischemic stroke" and "spontaneous intracerebral hemorrhage" stipulated in *Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke (2018)* and *Chinese Guidelines for the Diagnosis and Treatment of Intracerebral Hemorrhage (2019)* promulgated by the Cerebrovascular Disease Group of the Neurology Branch of the Chinese Medical Association. (2) First - onset stroke; (3) Patients aged between 18 and 80 years old without severe underlying diseases; (4) Disease course ranging from 1 month to 1 year; (5) No previous history of cognitive impairment and no family history of dementia; (6) In accordance with the diagnostic criteria in the *Expert Consensus on the Management of Post - Stroke Cognitive Impairment 2021*, the following conditions must be simultaneously met: 1) Dysfunction in at least one of the following five aspects: executive function, attention, memory, language ability, and visuospatial ability; 2) Capable of cooperating to complete the Montreal Cognitive Assessment Scale (MoCA) evaluation, with a score of < 26 points in the Beijing version of MoCA; (7) Voluntary participation in this study, and written informed consent signed by the subject or his/her family member.

Exclusion criteria

Exclusion criteria: (1) Patients with recurrent stroke during treatment sudden deterioration of condition or unstable vital signs; (2) Patients with severe visual auditory or speech impairments; (3) Patients with neuropsychiatric symptoms such as delusions hallucinations agitation or severe conditions like disturbance of consciousness that significantly affect their ability to cooperate with the study; (4) Patients with significant cognitive decline prior to stroke; (5) Cognitive impairment caused by other factors such as infection brain trauma medication nutritional deficiency or metabolic disorders; (6) Pregnant patients; (7) Patients participating in other clinical studies.

Design outcomes

Primary

MeasureTime frame
Montreal Cognitive Assessment (MoCA) Beijing Version;Mini-Mental State ExaminationMMSE;

Secondary

MeasureTime frame
Modified Barthel Index;complete spontaneous bowel movements;Wexner Constipation Score;Bristol Stool Scale;

Countries

China

Contacts

Public ContactRunqi Zhong

The Xiangya Hospital of Central South University, Jiangxi Branch

584893979@qq.com18229743119

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026