stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) In line with the diagnostic criteria for "acute ischemic stroke" and "spontaneous intracerebral hemorrhage" stipulated in *Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke (2018)* and *Chinese Guidelines for the Diagnosis and Treatment of Intracerebral Hemorrhage (2019)* promulgated by the Cerebrovascular Disease Group of the Neurology Branch of the Chinese Medical Association. (2) First - onset stroke; (3) Patients aged between 18 and 80 years old without severe underlying diseases; (4) Disease course ranging from 1 month to 1 year; (5) No previous history of cognitive impairment and no family history of dementia; (6) In accordance with the diagnostic criteria in the *Expert Consensus on the Management of Post - Stroke Cognitive Impairment 2021*, the following conditions must be simultaneously met: 1) Dysfunction in at least one of the following five aspects: executive function, attention, memory, language ability, and visuospatial ability; 2) Capable of cooperating to complete the Montreal Cognitive Assessment Scale (MoCA) evaluation, with a score of < 26 points in the Beijing version of MoCA; (7) Voluntary participation in this study, and written informed consent signed by the subject or his/her family member.
Exclusion criteria
Exclusion criteria: (1) Patients with recurrent stroke during treatment sudden deterioration of condition or unstable vital signs; (2) Patients with severe visual auditory or speech impairments; (3) Patients with neuropsychiatric symptoms such as delusions hallucinations agitation or severe conditions like disturbance of consciousness that significantly affect their ability to cooperate with the study; (4) Patients with significant cognitive decline prior to stroke; (5) Cognitive impairment caused by other factors such as infection brain trauma medication nutritional deficiency or metabolic disorders; (6) Pregnant patients; (7) Patients participating in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment (MoCA) Beijing Version;Mini-Mental State ExaminationMMSE; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Barthel Index;complete spontaneous bowel movements;Wexner Constipation Score;Bristol Stool Scale; | — |
Countries
China
Contacts
The Xiangya Hospital of Central South University, Jiangxi Branch