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Clinical efficacy evaluation and mechanism study of Fuzheng Qingre Lishui prescription for prevention and treatment of urinary tract infection recurrence and drug resistance

Clinical efficacy evaluation and mechanism study of Fuzheng Qingre Lishui prescription for prevention and treatment of urinary tract infection recurrence and drug resistance

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001768
Enrollment
Unknown
Registered
2025-09-16
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent urinary tract infection

Interventions

experimental group:Continuous low-dose antibiotics combined with traditional Chinese medicine formula for strengthening the body, clearing heat and promoting diuresis
control group:Continuous low-dose antibiotics + a decoction of traditional Chinese medicine for tonifying the body, clearing heat and promoting diuresis simulant

Sponsors

Wangjing Hospital China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1)Meet the diagnostic criteria of Recurrent Urinary Tract Infection TCM syndrome differentiation belongs to spleen and kidney deficiency dampness and turbidity type; 2) Female patients aged 18 = age =75 years; 3) The patient voluntarily participated in the clinical trial and signed the informed consen

Exclusion criteria

Exclusion criteria: 1) Patients with acute Urinary Tract Infection at the first attack; 2) Patients with congenital malformation of urinary tract hydronephrosis or calculus were found by imaging examination; Urethral syndrome: obstructive nephropathy caused by urethral valvular disease; Pelvic ultrasound or gynecological examination of urethral obstruction caused by uterine ptosis; Vagino-urethral fistula caused by dystocia; (4) Patients with severe heart liver or kidney damage or other serious underlying diseases requiring immediate treatment; People who are allergic to drugs; 6) Those who are participating in clinical trials of other drugs; 7) menstrual patients.

Design outcomes

Primary

MeasureTime frame
Urinary tract infection recurrence rate;Drug resistance rate;

Secondary

MeasureTime frame
Average time of recurrence of urinary tract infection;Urinary bacteria/urine culture conversion rate;Hospitalization rate;Detection rate of urinary bacterial biofilm/filamentous bacteria;The usage rate and types of antibacterial drugs;Antibiotic resistance spectrum of pathogenic bacteria;Traditional Chinese Medicine Syndrome Points;Quality of Life and Depression Anxiety Score;Rating of Drug Treatment Satisfaction Questionnaire Test Scale;

Countries

China

Contacts

Public ContactShiwei Liu

Wangjing Hospital China Academy of Chinese Medical Sciences

765058693@qq.com13810753021

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026