Unliquefiable semen
Conditions
Interventions
Control group:Semen Simulator Compound Xuanju Capsule
Experimental group:Shengjing Capsules +Compound Xuanju Capsule Simulation Agent
Sponsors
Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University
Eligibility
Sex/Gender
Male
Age
22 Years to 50 Years
Inclusion criteria
Inclusion criteria: (1)Male aged 22 to 50 (inclusive); (2) Patients who meet the diagnostic criteria for male Unliquefiable semen in Western medicine; (3) Patients who meet the diagnostic criteria for ShenYang deficiency syndrome in traditional Chinese medicine; (4) Voluntarily sign the informed consent form)
Exclusion criteria
Exclusion criteria: (1) Tuberculosis tumors urethral stricture interstitial cystitis neurogenic bladder or ureaplasma urealyticum sensation Dye; (2) There are gonadal dysplasia hypogonadism testicular atrophy cryptorchidism chronic epididymitis and retrograde conditions Ejaculation or no ejaculation Y chromosome microdeletion grade II or above varicocele urinary ract infection acute Patients with diseases such as seminal vesiculitis and acute prostatitis; (3) Patients with a history of mumps hernia or sexually transmitted diseases; (4) Patients with a history of reproductive organ surgery or trauma that affects their reproductive function; (5) Patients taking anti-epileptic anti-tumor or other drugs that may affect semen quality; (6) Have received infertility treatment measures semen liquefaction time treatment measures or sperm quality treatment measures within the past one month Patients undergoing quantitative treatment measures; (7) There are serious primary diseases of the heart liver kidneys hematopoietic system endocrine system respiratory system etc. Liver function ALT and/or AST are more than 1.5 times higher than the upper limit of the reference value and renal function Scr is higher than the upper limit of the normal value; (8) Combined with hypertension (Patients with persistent hypertension where systolic blood pressure >185 mmHg or diastolic blood pressure > 110 mmHg despite antihypertensive treatment), those with poor blood sugar control (HbA1c > 7.5%), Patients with obesity (BMI=27) or accompanied by metabolic syndrome; (9) Having a long-term and excessive habit of smoking and drinking or being exposed to high-temperature radioactive or toxic chemical environments but not Patients who can change or give up; (10) People with allergic constitutions or patients known to be allergic to the test drug and its components; (11) Patients with intellectual disabilities mental disorders etc. who may affect the evaluation of the trial; (12) Currently participating in other clinical trials or having participated in other drug clinical trials that have ended within less than three months (13)Patients with other conditions that the researcher deems inappropriate to participate in this study
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Proportion of subjects semen liquefaction time<60min;Proportion of subjects with semen liquefaction time<30min ;Changes of total sperm count, sperm motility from baseline;Total score of TCM syndromes and individual symptom scores;Efficacy of TCM medicine syndrome treatment; | — |
Primary
| Measure | Time frame |
|---|---|
| Proportion of subjects with semen liquefaction time<60min ; | — |
Countries
China
Contacts
Public ContactJia Liancheng
Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University
Outcome results
None listed