Asymptomatic Hyperuricemia with Dampness-Turbidity Accumulation Pattern
Conditions
Interventions
Treatment Group:Ganoderma Spore Powder 2g per dose BID (twice daily) Intervention code
Control Group:placebo
Sponsors
Zhejiang Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: According to the Integrated Traditional Chinese and Western Medicine Guidelines for Diagnosis and Treatment of Gout and Hyperuricemia (2023) Chinese Guidelines for Diagnosis and Treatment of Hyperuricemia and Gout (2019) and the 2013 Chinese Expert Consensus on Management of Hyperuricemia and Gout the following criteria apply: Mandatory criteria: Items (1) (4) (5) (6) Inclusion requires meeting either (2) or (3) (1) Age 18–80 years; (2) Serum uric acid (SUA) =420 µmol/L on two separate occasions under normal purine diet and fasting conditions; (3) Meeting TCM diagnostic criteria for dampness-turbidity accumulation pattern; (4) No use of medications affecting SUA within the past month (e.g. thiazide diuretics aspirin losartan glucocorticoids urate-lowering drugs fenofibrate statins); (5) Capacity to comprehend the study and voluntarily provide signed informed consent.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: (1) Presence of acute gout attack; (2) Diagnosis of gout-related nephropathy (e.g. uric acid nephrolithiasis chronic urate nephropathy acute uric acid nephropathy); (3) Requirement for regular use of antibiotics or other medications affecting uric acid levels; (4) Routine treatment with NSAIDs or corticosteroids; (5) Severe primary comorbidities involving cardiovascular cerebrovascular hepatic renal endocrine or hematopoietic systems; (6) Women who are planning pregnancy pregnant or lactating; (7) Known allergy to any component of the investigational product.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver Function;Serum Uric Acid Level;Plasma Metabolomic Differences;Renal Function;TCM Syndrome Score; | — |
Countries
China
Contacts
Public ContactMinchun Yang
Zhejiang Hospital
Outcome results
None listed