decreased ovarian reserve
Conditions
Interventions
electro-thumbtack needle group:electro-thumbtack needle
placebo group:sham electro-thumbtack needle
Sponsors
Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. The age range is 18-40 years old; 2. Meets the diagnostic criteria for DOR as follows: 1) AMH3.6; 3) The total number of follicles (AFC) in both basal sinuses is less than 7. Above 1)2)3) possess Any two of them can be diagnosed as DOR. 3. At least one side of the patient's fallopian tube is unobstructed; 4. The semen routine examination of the patient's spouse is normal; 5. Voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Chromosomal or genetic abnormalities in either the female or male partner; 2. Women with blocked fallopian tubes on both sides; 3. Have a history of ovarian surgery, such as ovarian teratoma or ovarian chocolate cyst surgery; 4. The female party suffers from uncorrected endocrine disorders such as simple hyperthyroidism or hypothyroidism, hyperprolactinemia, and pancreatic islet dysfunction Hormone resistance, diabetes, adrenal diseases, etc; 5. The woman has a clearly diagnosed autoimmune disease such as systemic lupus erythematosus, rheumatoid arthritis Antiphospholipid syndrome, Sjogren's syndrome, Hashimoto's thyroiditis, etc; 6. The female or male partner has a history of malignant tumors and has received treatment with radiotherapy and chemotherapy; 7. The woman has received acupuncture and moxibustion or press acupuncture treatment in recent 3 months; 8. Those who take traditional Chinese medicine decoctions or granules during treatment; 9. Men with abnormal semen examination; 10. Clear diagnosis of moderate or severe adenomyosis; 11. Clearly diagnose uterine fibroids with a diameter greater than 5cm; 12. I do not agree to sign the informed consent form for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Threatened miscarriage rate;Abortion rate;Biochemical pregnancy rate;clinical pregnancy rate;anti-Müllerian hormone;Number of basal antral follicles;Follicle-stimulatingHormone;Luteinizing Hormone;estradial;progesterone;Prolactin;testosterone;corticotropin releasing hormone;Norepinephrine;adrenaline;5-hydroxytryptamine;?- aminobutyric acid;dopamine;ß-Endorphin;Zung-Self-Rating Anxiety Scale?;Zung-Self-Rating Depression Scale?;36-Item Short Form Health Survey;Chinese Quality of Life Scale;Self-Rating Scale of Sleep?;Sleep Dysfunction Rating Scale;Pittsburgh Sleep Quality Index?; | — |
Countries
china
Contacts
Public ContactHuang dongmei
Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed