Lung cancer esophageal cancer breast cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Lung cancer breast cancer and esophageal cancer diagnosed by cytopathology; 2) Age =18 years and =75 years weight = 40kg; 3) Subjects have not received immunotherapy in the past 3 months and will not consider immunotherapy within 6 weeks after entering the group; 4) The subject has no intention and the lung liver kidney and hematopoietic system are dysfunctional; The definition is as follows: the absolute value of neutrophils (ANC)=1.5×109/L; Platelets = 100× 109/L; Hemoglobin = 90g/L; Total bilirubin =1.5× upper normal limit (ULN); AST(SGOT)/ALT(SGPT)=2.5× normal upper limit; Serum albumin = 30g/L; Serum creatinine < 1.5 times the normal upper limit; 5) KPS score =60; 6) The estimated survival time is =3 months; 7) Fully understand this study and sign the informed consent form voluntarily.
Exclusion criteria
Exclusion criteria: 1) Prepare for tumor immunotherapy during radiotherapy; 2) Patients with unstable brain metastases; 3) Pregnant and lactating women and women of childbearing age who are unwilling to take contraceptive measures; 4) patients with mental illness or mental retardation; 5) It is known that the drug is severely intolerant; 6) In the past 4 weeks or participating in other clinical trials; 7) Complicating one of the following symptoms: uncontrollable hypertension (uncontrollable hypertension after single drug treatment that is systolic blood pressure > 160mmHg or diastolic blood pressure > 100mmHg after single drug treatment) severe arrhythmia and cardiac function grade III-IV (NYHA classification method). 8) Patients with respiratory failure pulmonary fibrosis massive pericardial effusion pleural effusion and pulmonary infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cough, phlegm, fever, chest pain, wheezing, vomiting, diet, fatigue, nutrition;Tumor marker;Transforming growth factor ß1;Interleukin-6;Tumor necrosis factor-a; | — |
Countries
China
Contacts
Southwest medical university affiliated traditional Chinese medicine hospital