knee osteoarthritis
Conditions
Interventions
intervention groups:manipulative therapy
control group:Participants in the control group received no therapeutic intervention and were instructed to maintain their usual daily routines while avoiding structured lower extremity strength train
Sponsors
Shuguang Hospital affiliated with Shanghai University of TCM,
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Osteoarthritis of unilateral knee, contralateral knee clinically normal Age >50 years and <80 years Mild to moderate KOA severity (defined as a total WOMAC score of <48) Kellgren-Lawrence (KL) radiologic evaluation grade 0 to II#. No KOA-related pain management interventions (including medications) within 7 days prior to enrollment. Voluntary enrollment with written informed consent
Exclusion criteria
Exclusion criteria: Recent knee interventions (physiotherapy or intra-articular injections for KOA pain within 1 month) Significant comorbidities: -Major systemic diseases (e.g., NYHA Class III/IV heart failure, ESRD, uncontrolled diabetes) -Concurrent chronic pain disorders (e.g., fibromyalgia, neuropathic pain) Communication barriers affecting protocol compliance Positive ballottement test (indicating joint effusion) or Peripatellar skin lesions or infections Current participation in other clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| WOMAC pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| 6-MWT;Detection of proprioceptive power perception;The maximum isometric contractile force of the lower limb muscles; | — |
Countries
China
Contacts
Public ContactMin Fang
Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Outcome results
None listed