Rheumatoid Arthritis
Conditions
Interventions
HC:Extract peripheral blood mononuclear cells and plasma
RA :Extract peripheral blood mononuclear cells and plasma
Sponsors
Guangdong Provincial Hospital of Chinese Medicine University City Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for patients with rheumatoid arthritis: (1) Outpatient or inpatient COVID-19 patients aged 18-75, regardless of gender; (2) Meets the diagnostic criteria for rheumatoid arthritis proposed by the American College of Rheumatology (ACR) in 2021 and the European League Against Rheumatism (EULAR) in 2022; (3) Those who agree and sign the informed consent form. Inclusion criteria for healthy volunteers: (1) Individuals aged 18-75 who undergo health check ups in hospitals or communities, regardless of gender; (2) Confirm no autoimmune diseases and no joint pain symptoms; (3) Undiagnosed systemic diseases, not in a state of stress such as infection, pregnancy, childbirth, or trauma; (4) Those who agree and sign the informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria for wind related patients and healthy volunteers: (1) COVID-19 positive, H1N1 and other infectious diseases; (2) Merge with other rheumatic diseases (such as systemic lupus erythematosus, Sjogren's syndrome, systemic sclerosis, dermatomyositis, etc.); (3) Severe patients with extra articular manifestations (such as high fever, multiple rheumatoid nodules, interstitial pneumonia, etc.); (4) Cases with serious diseases such as cardiovascular, pulmonary, hepatic, renal, and hematopoietic systems; (5) Patients with severe infections, organ failure, or malignant tumors; (6) Pregnant or lactating women patients; (7) Individuals with a history of mental illnesses such as depression and anxiety, as well as those with cognitive impairment who cannot cooperate; (8) Patients with other diseases or lifestyle habits that may affect the research results, such as irregular sleep patterns, staying up late, insomnia, and female menstrual periods and pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| circadian genes;inflammatory cytokines; | — |
Countries
China
Contacts
Public ContactPanhudan
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed