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A Study on the Brain Gut Dual Regulation Mechanism of Tai Chi in Improving Chronic Fatigue Syndrome by Regulating 'Brain Metabolism/Brain Network- Gut Microbiota'

A Study on the Brain Gut Dual Regulation Mechanism of Tai Chi in Improving Chronic Fatigue Syndrome by Regulating 'Brain Metabolism/Brain Network- Gut Microbiota'

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001725
Enrollment
Unknown
Registered
2025-09-15
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic fatigue syndrome

Interventions

Cognitive Behavioral Therapy Group:Cognitive behavioral therapy for 8 weeks

Sponsors

Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria for chronic fatigue syndrome/Myalgic encephalomyelitis and have a Fatigue Scale-14 score = 7; (2) Aged 18-35 regardless of gender right-handed; (3) No special dietary habits, excluding individuals with digestive system diseases; (4) No prior experience in practicing Tai Chi; (5) Able to answer and complete questionnaires normally with good compliance; (6) No use of psychiatric medications within the past month; (7) No metal implants in the body and no contraindications for MRI; (8) The participant provides informed consent personally and voluntarily signs the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Those with clearly diagnosed organic diseases causing secondary fatigue or secondary fatigue caused by other factors; (2) Those previously diagnosed with mood disorders and various mental disorders such as delusional disorder anorexia nervosa etc.; (3) Those suffering from serious heart kidney lung liver brain and other major diseases with serious liver and kidney function abnormalities; (4) Those who are severely obese with a body mass index = [body weight (kg)/height2 (m)] > 45; (5) Those who have taken vasodilators, laxatives, antibiotics, or gut microbiome regulators in the past two months; (6) Pregnant lactating and menstruating women; (7) Those who cannot understand and cooperate with the examination or have other contraindications to magnetic resonance imaging examination such as claustrophobia; (8) Those who have found severe asymmetry of the cranial anatomy or definite lesions in the magnetic resonance imaging scan; (9) Those who have taken part in a similar neuroimaging test within one month.

Design outcomes

Primary

MeasureTime frame
Perceived Fatigue;

Secondary

MeasureTime frame
Health-Related Quality of Life;Subjective Pain Quality and Intensity;Sleep Quality;Depressive Symptoms;Dietary Habits;Severity of Gastrointestinal Symptoms;Stool Consistency;Efficency of Attentional Networks;Ability to Inhibit Cognitive Interference;

Countries

China

Contacts

Public ContactKuangshi Li

Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine

likuangshi89@hotmail.com+8613810333655

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026