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The effect of preoperative PC6 intradermal acupuncture combined with dexamethasone and palonosetron on preventing postoperative nausea and vomiting in bilateral orthognathic surgery: a research protocol for blind double-dummy randomized controlled clinical trial

The effect of preoperative PC6 intradermal acupuncture combined with dexamethasone and palonosetron on preventing postoperative nausea and vomiting in bilateral orthognathic surgery: a research protocol for blind double-dummy randomized controlled clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001713
Enrollment
Unknown
Registered
2025-09-11
Start date
2025-10-01
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting

Interventions

group A:Acupuncture stimulating Neiguan Point
group B:Acupuncture stimulating black point

Sponsors

Peking University Shenzhen Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: (1) Patients scheduled for bilateral orthognathic surgery (including Le Fort I osteotomy and bilateral sagittal split osteotomy); (2) male and female patients aged 18 to 64 years; (3) American Society of Anesthesiologists (ASA) physical status I-II; (4) patients informed about the study protocol with signed written consent.

Exclusion criteria

Exclusion criteria: (1) Presence of local scars or infections in acupuncture areas; (2) limb absence or peripheral nerve injury; (3) body mass index (BMI) >30 kg/m²; (4) history of substance abuse; (5) history of central nervous system disorders or psychiatric conditions; (6) requirement for postoperative intensive care unit (ICU) transfer; (7) current participation in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Nausea and vomiting 24 hours postoperatively;

Secondary

MeasureTime frame
Nausea and vomiting within 2 hours postoperatively;Nausea and vomiting 2 to 6 hours postoperatively;Nausea and vomiting 6 to 24 hours postoperatively;24-hour postoperative QOR-15 score;The total number of patient-controlled analgesia pump pressed by the patient within 24 hours;

Countries

China

Contacts

Public ContactZhitao Li

Peking University Shenzhen Hospital

lytow@qq.com15986636692

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026