Mild Cognitive Dysfunction
Conditions
Interventions
Treatment group (digital electric fire needling group):Digital electric fire needle Therapy
Control group (sham fire needle group):Sham fire needle treatment
Sponsors
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1: Meet MCI diagnostic criteria, and 18 points = Montreal Cognitive Assessment Scale (MoCA) <26 points 2: Age between 40 and 85 years 3: Be clear in consciousness and have sufficient visual, auditory and language skills to undergo neuropsychological assessment 4: The ability to live daily life has not decreased significantly, i.e. (ADL less than or equal to16 points) 5: The patient or family members informed consent for this study and signed an informed consent form
Exclusion criteria
Exclusion criteria: 1: Suffering from other diseases that can cause cognitive impairment (such as encephalitis, abnormal thyroid function, intracranial space-occupying lesions, mental history, Parkinson's history, etc.) 2: Unable to cooperate with all neuropsychological scale assessors (aphasia, severe vision and hearing impairment) 3: People with serious heart disease, liver and kidney, digestive system, tumors, etc. or severe systemic infections 4: Patients with a history of alcohol and drug abuse and long-term use of drugs that affect cognitive function, such as glucocorticoids, antipsychotics, sedatives and hypnotics, etc. 5: Those with coagulation dysfunction 6: Pregnant or lactating women 7: Participating in other clinical trials 8: Refusal to sign informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mini-Mental State Examination;Digit Span Test;Clock Drawing Task;Auditory Verbal Learning Test;Pittsburgh Sleep Quality Index;TNF-a;Brain-derived neurotrophic factor;IL-6;Nuclear factor ?B;IL-1ß; | — |
Countries
China
Contacts
Public ContactWang Shuxin
The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed