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Investigating the mechanism of action of Hugan Tiaoshen Formula to improve sleep disorders in patients with schizophrenia

Investigating the mechanism of action of Hugan Tiaoshen Formula to improve sleep disorders in patients with schizophrenia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001690
Enrollment
Unknown
Registered
2025-09-09
Start date
2025-02-28
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

schizophrenia

Interventions

Experimental group:Chinese herbal therapy
Control Group:conventional treatment

Sponsors

Wuxi Mental Health Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. meet the diagnostic criteria for schizophreniaEdition (DSM-5); 2 . Age in the range of 18-65 years; 3 . Voluntary participation in this study and co-operation in follow-up; 4 . Literacy level not lower than junior high school (usually with no less than 9 years of education);

Exclusion criteria

Exclusion criteria: 1. Those who meet the DSM- 5 criteria for any other psychiatric disorder; 2 .A history of convulsive electroconvulsive shock or modified electroconvulsive therapy within 6 months prior to enrolment; 3 . Organic brain disease history of seizures or history of head trauma; 4 . women during pregnancy and lactation; 5. those with poorly controlled physical illnesses who are unable to co-operate with study follow-up .

Design outcomes

Primary

MeasureTime frame
sleep electroencephalogram (SEEG);

Secondary

MeasureTime frame
Mental Disorder Symptom Assessment;Transcriptomics;Metabolomics;Gut Microbiota 16S Sequencing;Oral microbiota;

Countries

China

Contacts

Public ContactZixuanHuang

Wuxi Mental Health Center

7242808008@stu.jiangnan.edu.cn18306178866

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026