Pancreaticoduodenectomy in elderly patients
Conditions
Interventions
Observation Group:The observation group began to receive SHL-OL (Heilongjiang Linbao Pharmaceutical Co., Ltd., batch number: Z23020924
specification: 10 milliliters per bottle) 30ml via nasogastric tube 12 hours after surgery (heated to 37°C, with the tube clamped for 1 hour after administration), while the same EEN regimen was used.
Control Group:On the basis of routine postoperative treatment, 500ml of 5% glucose and sodium chloride solution was administered via nasogastric tube at 12 hours after surgery, and nutritional solutio
Sponsors
Jining Medical University Affiliated Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: Age 60-80 years; preoperative diagnosis is clear; malnutrition exists and requires enteral nutrition support; patient voluntarily accepts the treatment plan of this study and signs an informed consent form.
Exclusion criteria
Exclusion criteria: Cardiopulmonary renal function, coagulation indicators are abnormal, gastrointestinal function is intolerant; allergic to the components of Shuanghuanglian oral liquid or enteral / parenteral nutrition solution; voluntarily refuse to accept the treatment plan of this study; meet the inclusion criteria but did not implement enteral nutrition as planned after inclusion.During the treatment process, patients voluntarily withdraw or encounter unexpected circumstances that prevent them from continuing treatment; during the trial, serious adverse reactions or special physiological changes occur, making it unsuitable to continue the trial, which are recorded as adverse events; patient information is incomplete, affecting the judgment of effectiveness and safety.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stress Indicators 72 hours after Surgery (Cortisol [COR] Adrenocorticotropic Hormone [ACTH] Epinephrine [EPI]);Time of First Defecation;Inflammatory Indicators 72 hours after Surgery (C-reactive Protein [CRP] Interleukin-6 [IL-6]); | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life;Patient Comfort and Satisfaction;Occurrence of Adverse Events; | — |
Countries
China
Contacts
Public Contactzhangpeilu
Jining Medical University Affiliated Hospital
Outcome results
None listed