subthreshold depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Experimental Group (Subthreshold Depression): (1) Meeting diagnostic criteria for subthreshold depression; (2) STDS score between 65-79; (3) Age 18-50 years any gender; (4) Normal corrected or uncorrected vision without color blindness; (5) Willing and able to complete all assessments and provide informed consent. Control Group (Healthy Controls): (1) Meeting WHO health standards; (2) STDS score <65; (3) Age 18-50 years any gender; (4) Normal corrected or uncorrected vision without color blindness; (5) Willing and able to complete all assessments and provide informed consent.
Exclusion criteria
Exclusion criteria: (1) Exclusion Criteria for the Experimental Group (Subthreshold Depression Group): Individuals meeting any of the following criteria were excluded: 1) Those with severe psychiatric disorders; 2) Those with cognitive impairment or consciousness disorders; 3) Patients diagnosed with depression caused by organic diseases, psychoactive substances, or non-addictive substances; 4) Those with severe diseases in other systems requiring treatment; 5) Those with drug or alcohol dependence issues; 6) Individuals with pacemakers, stents, metal implants or foreign bodies, or claustrophobia; 7) Patients with high fever (body temperature above 38.5°C) or early pregnancy (within the first 3 months of pregnancy); 8) Those unable to comprehend or cooperate with the study's objectives, or unable to comply with and tolerate the study protocol. (2) Exclusion Criteria for the Control Group (Healthy Group): Individuals meeting any of the following criteria were excluded: 1) Those with a history of mental illness or drug abuse; 2) Those with drug or alcohol dependence issues; 3) Individuals with pacemakers, stents, metal implants or foreign bodies, or claustrophobia; 4) Patients with high fever (body temperature above 38.5°C) or early pregnancy (within the first 3 months of pregnancy); 5) Those unable to comprehend or cooperate with the study's objectives, or unable to comply with and tolerate the study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Multimodal Brain MRI Data; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in subthreshold depressive symptoms (STDS);Five-State Personality Inventory (FSPI);Syndrome Element Differentiation Scale for Depression (SEDS) scores;Pay attention to biased behavioral indicators; | — |
Countries
China
Contacts
Beijing University of Traditional Chinese Medicine Shenzhen Hospital (Longgang)