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Brain Mechanism Effects of Traditional Chinese Medicine Emotion Stimulation Intervention on Subthreshold Depressive Populations with Different TCM Syndrome Differentiation Types Based on Magnetic Resonance Imaging (MRI) Technology

Research on the Brain Effect Mechanism of Traditional Chinese Medicine Emotional Stimulation Intervention for Subthreshold Depression with Typical Deficiency Deficiency Syndrome Based on Magnetic Resonance Imaging Technology

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ITMCTR
Registry ID
ITMCTR2025001682
Enrollment
Unknown
Registered
2025-09-05
Start date
2025-09-05
Completion date
Unknown
Last updated
2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

subthreshold depression

Interventions

Control group: Healthy population group:not have
Experimental Group : Subthreshold depression group :Traditional Chinese Medicine Emotional and Mood Induction

Sponsors

Beijing University of Traditional Chinese Medicine Shenzhen Hospital (Longgang)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Experimental Group (Subthreshold Depression): (1) Meeting diagnostic criteria for subthreshold depression; (2) STDS score between 65-79; (3) Age 18-50 years any gender; (4) Normal corrected or uncorrected vision without color blindness; (5) Willing and able to complete all assessments and provide informed consent. Control Group (Healthy Controls): (1) Meeting WHO health standards; (2) STDS score <65; (3) Age 18-50 years any gender; (4) Normal corrected or uncorrected vision without color blindness; (5) Willing and able to complete all assessments and provide informed consent.

Exclusion criteria

Exclusion criteria: (1) Exclusion Criteria for the Experimental Group (Subthreshold Depression Group): Individuals meeting any of the following criteria were excluded: 1) Those with severe psychiatric disorders; 2) Those with cognitive impairment or consciousness disorders; 3) Patients diagnosed with depression caused by organic diseases, psychoactive substances, or non-addictive substances; 4) Those with severe diseases in other systems requiring treatment; 5) Those with drug or alcohol dependence issues; 6) Individuals with pacemakers, stents, metal implants or foreign bodies, or claustrophobia; 7) Patients with high fever (body temperature above 38.5°C) or early pregnancy (within the first 3 months of pregnancy); 8) Those unable to comprehend or cooperate with the study's objectives, or unable to comply with and tolerate the study protocol. (2) Exclusion Criteria for the Control Group (Healthy Group): Individuals meeting any of the following criteria were excluded: 1) Those with a history of mental illness or drug abuse; 2) Those with drug or alcohol dependence issues; 3) Individuals with pacemakers, stents, metal implants or foreign bodies, or claustrophobia; 4) Patients with high fever (body temperature above 38.5°C) or early pregnancy (within the first 3 months of pregnancy); 5) Those unable to comprehend or cooperate with the study's objectives, or unable to comply with and tolerate the study protocol.

Design outcomes

Primary

MeasureTime frame
Multimodal Brain MRI Data;

Secondary

MeasureTime frame
Improvement in subthreshold depressive symptoms (STDS);Five-State Personality Inventory (FSPI);Syndrome Element Differentiation Scale for Depression (SEDS) scores;Pay attention to biased behavioral indicators;

Countries

China

Contacts

Public ContactTan Xi

Beijing University of Traditional Chinese Medicine Shenzhen Hospital (Longgang)

tanxi@bucm.edu.cn13810048804

Outcome results

None listed

Source: ITMCTR (via WHO ICTRP) · Data processed: Feb 4, 2026